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Toplep (Topiramate)

Toplep is a medicine called an anticonvulsant. It is used to control and prevent certain types of seizures. It is often used to control and prevent tonic-clonic seizures, also called grand mal seizures. It may also be used to treat partial seizures. You may also hear Toplep called by one of its brand names, Toplep.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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The surface treated nanowires are then dispersed on a receiver substrate where the passive electrodes are structured, followed by printing of a composite solid polymer electrolyte (CSPE), chosen as the gate insulator. Therefore, addressing the nutrition needs of adolescents could be an important step toward breaking the vicious cycle of intergenerational malnutrition, chronic diseases, and poverty. Proper QC of phenotypes before proceeding to the association analysis is critical to ensure control of type I and II errors, reliable effect estimates and consistent results between studies.

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Suppurative-necrotic complications of rheumatoid arthritis in childhood The effect of phototherapy on urinary calcium excretion in newborns.

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The biopsies were stained with PAS as well as immunostained for PCNA (a cell proliferation marker), monocytes/macrophages, types I and IV collagen, laminin, s-laminin, fibronectin, heparan sulfate proteoglycan and entactin/nidogen. The combination of minimized sample volume and single molecule detection yielded a detection limit of 39 fM (831 molecules in 35.4 nl assay volume) for target DNA and 16 fM (338 molecules) for target RNA after 1h on-chip hybridization. We expressed HCV core protein using a tetracycline-inducible expression system in HeLa cell lines. Prognostic significance of fascin overexpression in human esophageal squamous cell carcinoma.

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A new definition and properties of the similarity value between two protein structures. We suggest that the observed switching is the electrical manifestation of the optical blinking phenomenon, commonly observed in semiconductor quantum dots. Both groups showed statistically significant improvements in periodontal clinical parameters, reduction in TCI, organoleptic scores, and in CH3SH levels between times. In the second part, perioperative changes in coagulation-related factors, including the thrombin-antithrombin complex(TAT) and platelet aggregation activity, were serially characterized in 82 individuals randomly chosen from the consecutive patients.

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In the present study our aim was to investigate whether plasma ADMA levels are predictive of brachial artery endothelial function in a prospective setting. Guanethidine sulphate induces destruction of peripheral sympathetic neurons and infiltration of mononuclear cells in rat sympathetic ganglia. Furthermore, c-Myc/Bin1 interaction can be inhibited by phosphorylation of c-Myc at Ser62, a functionally important residue found within the c-Myc SH3-binding motif. Different varieties of hops vary in amount and composition of hop acids.

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Linearized molecules of DNA have been used to get their genomic integration but the transformation efficiency drops extremely. Owing to the strongly enhanced evanescent field interaction with monolayer graphene, we could realize an efficient control of modulation depth in the graphene saturable absorber by optical means through cross absorption modulation method. Images were reconstructed using two modes: polychromatic and 70 keV monochromatic. Rhythmical jaw movements (RJM) were observed to be associated with these rhythmical potentials. Use of transendoscopic contact neodymium:yttrium aluminum garnet laser to drain dorsal epiglottic abscesses in two horses.

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Aberrant migration of NCCs results in a wide variety of congenital birth defects including craniofacial abnormalities. Trust-level risk evaluation and risk control guidance in the NHS East of England. Guidelines for triaging patients for cardiac catheterization recommend a risk assessment and noninvasive testing. Letter: Apparently primary bilateral external iliac dissection in a young woman

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To document ultrastructural changes of brain, spinal cord, skeletal muscle, jejunum and lung of EV71 infection mouse model, and to explore the myotropism and pathogenesis of EV71 in nervous system. oleifera seeds contain the lectins cmol and WSMoL, which are carbohydrate-binding proteins that are able to reduce water turbidity because of their coagulant activity. Capillary-like structure (CLS) formation at 7day was significantly better with the groups containing higher doses of hFDM compared to the Col group (control).

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However, recent studies suggest that a significant proportion of patients suffer some degree of hypopituitarism. The anesthesiologist who cares for children with cancer or for survivors of childhood cancer should understand what effects cancer and its therapy can have on various organ systems. 40 primary care nursing centres (clusters) in Victoria, Australia. To get mechanistic insight into the DNA strand-exchange reaction of homologous recombination, we solved a filament structure of a human Rad51 protein, combining molecular modeling with experimental data.

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Rotavirus is an important cause of acute gastroenteritis in infants. Selection of animals for the beta-lactoglobulin B-allele may enable the production of milk naturally enriched for casein, thus allowing a potential increase in the yield of cheese. The objectives of this study were to (a) translate the EDRSQ to French (EDRSQ-F), (b) assess the psychometric properties of this French version, and (c) establish normative data for a non-clinical sample. These results show the existence of significant differences between the 31phosphorus spectrum of tumors and neck muscle, but also between the tumors and their contralateral sides. Seasonal autoregressive models captured a substantial amount of dengue variability, but better models are needed to improve dengue forecasting.

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These data suggest that PGD2 possesses the ability to modulate responses to nerve stimulation and pressor hormones by both pre- and post-junctional actions in the feline mesenteric vascular bed. Advances in RNA interference (RNAi) and transcription studies have facilitated the application of systematic cell-based loss- or gain-of-function and cell response screening that enable genome-wide analysis of cell factors involved in viral replication and disease. In all three, the imaging finding was predated by clear clinical abnormalities.

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Prescription drug monitoring programs (PDMP) can be used to assist physicians identify individuals at increased risk to misuse or abuse opioids. Psychotherapy likely provides improvements in psychobiological stress responses and decreases the occurrence of suicidal ideation in patients with AD. Further development of this therapy is now dependent on new clinical trials with more complex study designs. Microfluidic systems and proteomics: applications of the electrocapture technology to protein and peptide analysis.

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On the stoichiometry and reversibility of interaction between Neurospora protease I and its inhibitor. These findings suggest that pre-treatment with glycerol may enhance the effectiveness of radiotherapy against oral squamous cell carcinomas bearing an mp53 gene mutation. Nevertheless, the classification performance based on such reduced data was not significantly better than the classification of data reduced by mass univariate selection using a t-test or unsupervised multivariate reduction using principal component analysis. Although the use of perioperative nerve blockade for TKA may improve short-term outcomes, the analyzed types of blocks do not appear to decrease the risk of persistent opioid use in the longer term.

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ART performed to a very similar accuracy as manual tracking and Ethovision (a commercially available alternative), with average differences in coordinate points of 0.6 and 0.8mm, respectively. The aim of this study was to evaluate the surgical and obstetrical outcomes of patients with early cervical cancer who underwent laparoscopic radical trachelectomy and pelvic lymphadenectomy. Increasing evidence also points to a role in the wiring of the gut-brain axis. Selection of disposable personal protective equipment for work with samples containing highly pathogenic microorganisms

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The patient profile of this NET clinic has a higher degree of non-musculoskeletal patients than that usually reported in non-NET chiropractic offices, and other forms of chiropractic previously described in the literature. Surface roughness is studied experimentally by making use of the statistical properties of dichromatic speckle patterns. Central venous catheterization (CVC) is a commonly performed intraoperative procedure. To that end, we hypothesize that certain interventions designed to reduce injecting-related risk behaviors may also reduce the risk that PWID expose and introduce others into injecting.

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The purpose of this article is to understand the derivation of clinical guidelines, to learn how to resolve controversy or differences between guidelines and clinical practice, and to learn steps to apply the guidelines to an individual institution or clinical practice. With large amounts of experimental evidence supporting theories of either gold nanoparticles or sub-nm gold species being active, it was recently proposed that a size-dependent activity hierarchy should exist.

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Severe intestinal ulcers resulted following oral administration of indomethacin in either vehicle at daily 3-4-mg/kg doses, but did not result from EPCMPV formulations, whether dosed for 4 days or 14 days. Noise-induced hearing loss following a broadband noise exposure has been characterized by a notch in the audiogram in the 3.0 to 6.0 kHz range.

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Clinical data of nine patients with FPUB treated between June 1985 and January 2009 at Peking Union Medical College Hospital were analyzed. These patients underwent follow-up during their course of therapy, ranging from 3 weeks to 15 months. A549 cells were respectively treated with pCMV6-MYC-KL or klotho specific shRNAs.

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Atmospheric pollution is increasingly responsible for chronic airway disease. This is demonstrated using molecular dynamics to simulate an ensemble of over 100 folding trajectories. To retrospectively investigate the impact of prostate specific antigen (PSA) level after neoadjuvant androgen- deprivation therapy (ADT) on biochemical relapse-free survival in patients with prostate cancer who received radical radiotherapy (RT).

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The challenge organism was reisolated from all the infected quarters and the ensuing inflammatory response produced a chronic mastitis with a permanent drop in milk yield. Foreign body reactions to polyurethane covers of some breast prostheses.

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The relationship between FMD and cognition in individuals without cerebrovascular disease has yet to be systematically reviewed. With same channel width, the influence of different nanopore shapes can be approximately omitted if the nanopore is small enough (smaller than 0.5 times EMFP in this paper). For in vivo bioavailability studies rabbits were used as animal models. Genetic structure and differentiation in cultivated fig (Ficus carica L.).

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Percutaneous closure of femoral artery access sites in endovascular stent-graft treatment of aortic disease. The role of the bacterial microbiota on reproductive and pregnancy health. EGID is a previously unrecognized comorbid disease in pediatric patients with PHTS. This study evaluated the prognostic value of the Para pharyngeal space involvement in nasopharyngeal carcinoma T 2 disease (UICC 1997 classification).

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Ethnic and diet-related differences in the healthy infant microbiome. Research performed over the last decade revealed that cells surrounding the central canal of the adult spinal cord and forming the ependymal layer acquire stem cell properties either in vitro or in response to injury. A microassay for heme oxygenase activity using thin-layer chromatography. Familial and sporadic subtypes of early-onset Obsessive-Compulsive disorder. EGFR mutation-specific antibodies in pulmonary adenocarcinoma: a comparison with DNA direct sequencing.

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Considerable interindividual differences with respect to maximal impairment following a particular drug treatment were observed, with poor correlation between individual maximal impairments and individual peak plasma concentrations of the drug. This article reviews research findings pertaining to screening and monitoring NP status in MS as well as the clinical meaning of NP impairment.

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Here, we provide a brief, selective review of challenges to personalisation of the management of MS and suggest an agenda for stakeholder engagement and research to address them. Importance of physical parameters for the effectiveness of radiofrequency catheter ablation Are amino acid patterns necessarily abnormal in epileptic brains? The aortography revealed aortic dissection and a fistulous communication into the right atrium.

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Our purpose was to determine whether oral etretinate at 1 mg/kg can be combined with 35 Gy of radiation without intensifying or prolonging the radiation reaction and to determine the relapse-free survival rate. Are there differential effects of managed care on publicly insured children with chronic health conditions? Nevertheless, both WEHI-231, WEHI-231.7 and their delta-transfectants demonstrate the ability to induce growth arrest following sIgM but not sIgD crosslinking. In the absence of contraindications, TEE should generally be performed during aortic surgery and endovascular aortic procedures.

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The pangolin is a Pholidota mammal with large keratin scales protecting its skin. Lesions of the rat postsubiculum impair performance on spatial tasks. PHA-739358 inhibited proliferation and induced apoptosis independently of Bcr/Abl, the T315I mutation, or presence of the tumor suppressor p53, but the degree of effectiveness varied between different ALL samples. A labile period in the determination of the anterior-posterior axis during early neural development in Xenopus.

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Pseudotuberculosis has been experimentally shown to start as generalized infection due to the rapid (during 10-15 minutes) penetration of the infective agent through the epithelium of the mouth cavity, the small intestine, the urinary bladder, conjunctiva, pulmonary alveoli and vascular walls into the blood and then into internal organs. Thumb metacarpophalangeal capsulodesis: an adjunct procedure to basal joint arthroplasty for collapse deformity of the first ray. The role of SGK-1 in angiotensin II-mediated sodium reabsorption in human proximal tubular cells. Acute toxicity was evaluated for gold, silver and iron oxide (IO)NPs, and the latter were additionally subjected to a multiparametric analysis to assess sublethal effects. The depression of the reproduction of the human immunodeficiency virus by the use of Bogomolets antireticular cytotoxic serum

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Shoulder motion was measured and functional outcomes were obtained using the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire. It is concluded that the reported occupational hazards in industries where trafficked persons are forced into are not specific to trafficked persons as they affect all labourers. Aqueous extracts of human thymus were found to stimulate the DNA synthesis of human thymocytes in vitro. Instead of classical signs of tamponade, however, the signs of posterior wall infarction were most prominent.

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Characteristics of violence against children in a Brazilian capital. While the age-specific rate of gain of infection was generally unchanged in the IVM area, an increase in all age classes was observed after 1985 in the comparison area, where the Annual Transmission Index was high during the previous years. Freehand SPECT with 3D navigation is a valuable tool in RSL for both single and multiple implanted I-seeds in breast-preserving cancer surgery.

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The accuracy and completeness of the Wessex Cancer Register for this particular cancer was assessed and further sources of registration identified. The use of Piromen, a polysaccharide complex of Pseudomonas aeroginosa, has been investigated in 21 calves by a test of marrow granulocyte reserves. Carnitine protects the intestine against reperfusion injury in rats. Estrogen alleviates cognitive dysfunction following transient brain ischemia in ovariectomized gerbils. Our aim was to compare data from 2006 to 2013 with a previously published manuscript assessing the 2001-2005 period.

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To identify correlates of risky sexual behavior among adolescents surviving childhood cancer. Transurethral resection of the bladder tumour (TURBT) for non-muscle invasive bladder cancer: basic skills. Pain scores (patient-rated scores from 0 to 10) were extracted from the medical record, if available. To compare the effects of cervical versus thoracic thrust manipulation in patients with bilateral chronic mechanical neck pain on pressure pain sensitivity, neck pain, and cervical range of motion (CROM). A beta42 coexisted with the oxidative damage markers malondialdehyde, 8-hydroxydeoxyguanosine, heme oxygenase-1, and nitrotyrosine in abnormal neurons.

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In a secondary analysis, the factors associated with worse QOL outcomes among the VAD patients were also investigated. Effects of Acute Sleep Deprivation Resulting from Night Shift Work on Young Doctors. However, recent epidemiological estimates differ depending on the population studied and methods used. The virtual slide(s) for this article can be found here: Myocardial fibrosis is commonly detected by histology, and is associated with clinical vulnerability to adverse outcomes.

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In rats treated with methotrexate sodium, there was a higher uptake of (99m)Tc-DMSA in the bones, stomach and intestine, a higher uptake of (99m)Tc-DPD in the bones, intestine, blood and muscle, a lower uptake of (99m)Tc-tin colloid in the liver and a lower accumulation of (99m)Tc-MAA in the lungs. Among the different metal biokinetic parameters, dietary assimilation efficiency and elimination rate appear to be most impacted by MT induction.

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Consistent with the Dyadic Biopsychosocial Model of Marriage and Health, partner stress has direct associations with waist circumference among couples and this link is moderated by negative marital quality. All these processes are responsible for the biogenesis of membrane proteins that mediate essential functions of the cell such as selective transport, energy conversion, cell division, extracellular signal sensing, and motility.

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After a 6-minute acclimation period, baseline blood gas values and transpulmonary pressure were measured. This requirement originated and was developed as an ethical issue.

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As pansec dosage expected, disruption of the Stat4 gene reduced production of Th1 and Th2 cytokines, but surprisingly exacerbated Con A-induced liver injury. Overall, we suggest that in obese subjects altered adipokine levels play a key role in common carotid atherosclerosis both directly and through haemostatic parameters. It is effective even when intravenous agents fail to control myoclonus. Screening identified a new Tsip1-interacting protein, Nicotiana tabacum Tsip1-interacting ferredoxin 1 (NtTfd1), and binding specificity was confirmed both in vitro and in vivo.

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This study had as objective to reflect about incubate of learning in the nursing as an innovation in the teaching of the care. It is time to stop interrupting anticoagulant therapy for oral surgery. Palmitate increased expression of the BH3-only proteins PUMA and Bim, which was attenuated by palmitoleate. Despite frequently leading to emergency department (ED) visits, little evidence exists to characterize the nature of ED visits or to guide carbamazepine and alcohol metabolism rates its treatment in the ED.

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Since the migration of some of the hazardous compounds from the packaging materials into the pastries under normal conditions was indicated, it is recommended that the procedure for preparing pastry packaging materials should be reconsidered and improved. Polymorphisms in LEPR, PPARG and APM1 genes: associations with energy intake and metabolic traits in young children. During its young history the science of nursing established a variety of different nursing theories in the United States. Sustained efficacy and immunogenicity of the HPV-16/18 AS04-adjuvanted vaccine up to 7.3 years in omeprazole generic walgreens zyrtec young adult women.

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Beers criteria are a set of standard criteria for guiding drug prescription in elderly. These results suggest that only cortical responses were affected by the different histories of deafness of the ears. So far, studies that compare different techniques to remove pedicle screws that are suspected to penetrate the aorta are missing. An innovative clarithromycin 500 mg er tabs approach, the phonathon, may be a potentially important recruitment strategy. With the use of optical trapping, a single vesicle that had attoliters (10(-18) liters) of volume was introduced into the tapered inlet of a separation capillary.

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In comparison with the rest-obstructive profile, latent and non-obstructive HCM patients seem to share a similar exertional behaviour characterized by a greater increment of cardiac index during exercise and a minor impairment of buspirone high dose studies exercise tolerance. Using genome-wide profiling we establish a unique within Africa population substructure.

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Although there is no consensus about a specific relationship of depression with certain cancer types, some authors have proposed augmentin 375 mg tablets dosage that depression constitutes a risk factor for cancer. Glyptosternoid fishes (Siluriformes), one of the three broad fish lineages (the two other are schizothoracines and Triplophysa), have a limited distribution in the rivers in the Tibetan Plateau and peripheral regions. Hearing thresholds among young professional divers: a 6-year longitudinal study. ATP III and JNC 7 were used for defining metabolic syndrome and hypertension.

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One-hundred and six adults with depression were randomized into a CAT group or visual art (VA) control group for six 2.5-h weekly sessions. Obesity prevention, like treatment, is a complex and multifactorial process. The aim of this study was to assess the knowledge and attitude among general dental practitioners towards minimally invasive dentistry in Riyadh and AlKharj cities of Saudi Arabia. In addition, shear-induced augmentation of functional markers of the mature endothelial phenotype such as uptake of acetylated low-density lipoproteins and formation of capillary-like structures on Matrigel. Five dimensions of the new HIV/AIDS-targeted quality of life instrument (overall function, disclosure worries, health worries, financial worries, and duloxetine dosage forms of spironolactone life satisfaction) exhibited good psychometric properties, including low ceiling/floor effects, good internal consistency, and evidence for construct validity.

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Autofluorescence imaging findings in long-standing chorioretinal folds. For 422 stroke patients, assessments were made vantin suspension storage within two weeks of the index event.