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Topirol (Topiramate)

Topirol is used alone or with other medications to treat certain types of seizures including primary generalized tonic-clonic seizures (formerly known as a grand mal seizure; seizure that involves the entire body) and partial onset seizures (seizures that involve only one part of the brain). Topirol is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topirol is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur. Topirol is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Advance directives and what attracts elderly people to particular brochures. To investigate three families and one sporadic case with a recessively inherited ataxic syndrome. Special attention was given to the influence of high temperatures on the solvent effects. In vitro antioxidant and antidiabetic activities of zinc oxide nanoparticles synthesized using different plant extracts. Actinic cheilitis, a common disease caused by chronic solar exposure and tobacco use, is considered a premalignant lesion with potential to develop into squamous cell carcinoma.

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The aim was to examine social and physical correlates of blood pressure in 15 year olds. Although the total cancer as well as the cancer for trachea, bronchus and lung for the entire female cohort was not significantly elevated, trend analysis by calendar-year interval suggested an upward trend.

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We evaluated the clinicopathological significance of these ligands and receptors in TEpC and spindle-shaped stromal cells, not associated with the vasculature, to determine their impact on prognosis of patients with early-stage breast cancer. Using small interfering RNA knockdowns and peptide-blocking strategies, we demonstrated that trans-Ly108 interactions between dendritic cells and iNKT cells are critical for robust activation.

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The SPT wheal responses for allergens previously testing negative were enhanced after a stressor. In vivo versus simulation training: an interactional analysis of range and type of training exemplars. A potable water treatment plant, supplied from a low NOM (natural organic matter), low turbidity source with precoagulation and two-stage pressure sand filtration, had a MF (microfiltration) membrane process added to meet UK Water Regulations.

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The obstetrician should be aware of the possibility of addiction and its effects on pregnancy, and when possible, appropriate management should be initiated. An immunohistochemical approach for the radiosensitivity in carcinoma of the uterine cervix Future studies using ad libitum e-cigarette use bouts would facilitate understanding of e-cigarette toxicant yield. The unbiased sampling of the human transcriptome achieved by MPSS supports the idea that most human genes have been mapped, if not functionally characterized.

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This study was undertaken to determine what optimal levels of suction pressure were necessary to provide good drainage volume and obliteration of any dead space and also to determine the prevalence of clotting and complications secondary to various levels of suction pressure. We report the case of a 29-year-old female who presented with galactorrhea and irregular menstrual periods. In this study we demonstrate that antitumor CTL repertoire restricted to a single MHC class I allele is higher in homozygous than in heterozygous mice.

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Research is lacking in many aspects of AD, especially their biological underpinnings and treatments. Thus, we have uncovered a Pitx2-Sox2-Lef-1 transcriptional mechanism that regulates DESC homeostasis and dental development. Our study brought essential genetic clarifications, which have implications for conservation strategies in identifying distinct lineages across which birds should not be artificially moved through exchange/reintroduction schemes.

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Neonatal exposure to bisphenol A alters estrogen-dependent mechanisms governing sexual behavior in the adult female rat. Structural analysis of the specific capsular polysaccharide of Rhodococcus equi serotype 2. Implications of the present findings for our understanding of the development of bipolar disorder, as well as for informing early interventions, are discussed. Some definitions only consider those drugs used for the treatment of serious diseases or drugs for which no alternative is available. On postoperative day 6, the patient presented with blurred vision due to severe vitreous opacity in the right eye.

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This examination of two health-related social marketing programs operating simultaneously in the same country can highlight the factors that contribute to successful programs. To investigate whether the advancement of puberty in response to high-fat diet (HFD) results from a concomitant increase in LH pulse frequency and kisspeptin (Kiss1) and neurokinin B (NKB) signaling in the hypothalamus, blood samples were collected on postnatal day (pnd) 28, 32, or 36 for LH measurement and vaginal opening monitored as a marker of puberty in female rats fed with HFD or standard chow from weaning. The opportunities and challenges of the MSSP ACO program: a report from the field.

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Herfindahl-Hirschman Index (HHI) was used to measure the size of firms in relation to the industry to determine the amount of competition. Generation of high-affinity antibody against T cell-dependent antigen in the Ganp gene-transgenic mouse. Identification of reliable biomarkers is essential for early diagnosis and adaptive treatment of diseases, especially cancer.

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Effects of morphine-nitrous oxide anesthesia on cerebral autoregulation. Uptake of cesium and strontium ions by artificially altered phlogopite. We applied the model to data from the Ontario Breast Screening Program in Canada.

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Gastric acid secretion increased when LHA unit activity increased. Such systemic immunity lasted for more than 20 weeks after intraperitoneal injection of a small dose of bacilli, but was completely abolished during the course of a heavy systemic MLM infection. If past history and/or laboratory tests suggest gastrointestinal (GI) dysfunction they should also undergo small intestinal biopsy even if they do not have GI tract symptoms.

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Fluorescence in situ hybridization reveals over 50 hobo hybridization sites scattered throughout the flr(3)/Ser genome. A multiple-entry electronic key based on morphological, cultural, and beta-tubulin sequence data was developed to facilitate routine species identification. A diagnosis of Munchausen syndrome by proxy was made after the demonstration of egg albumin, diphenhydramine and phenothiazine metabolites in her urine.

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Radiation absorbed by interventional cardiologists is a frequently under-evaluated important issue. It highlights the role of current and emerging antifungal agents, including the lipid amphotericin B products, echinocandins and triazoles.

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On releasing the ischiofemoral ligament, the greatest gain in range of motion was that of internal rotation. The HCK and HUVEC were incubated with GHSA, IL-1 beta and TNF-alpha. For lipids with acyl moieties of similar length, the surface pressure and area at monolayer collapse can be accurately predicted from data obtained at lower surface pressure.

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The management of intractable hemoptysis, short of surgery, is poorly defined. Nutrition, circadian rhythm disturbance, psychological state, pain and other medical problems impact on physical abilities and increase the occurrence of accidents.

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The topographic distribution of 3H-testosterone and/or its metabolites in brains of Bramblings (Fringilla montifringilla L.) was studied autoradiographically and the intensity of labeling was estimated semi-quantitatively. Our approach to quantifying the association between tagged proteins is to use an object-based method where the exact match of object locations is not assumed. Sufficient design conditions are provided in terms of linear matrix inequalities for both cases. The results of our experiments conducted with 15 human livers harvested from the patients having some form of liver disease show that the proposed approach can successfully differentiate the level of fibrosis in human liver. The manometric and cineradiographic features of 14 patients with oropharyngeal dysphagia are described.

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This present study evaluated the chemopreventive efficacy of different parts of R. Aggressive resection of insular HGG is predictive of improved OS and PFS. Long-lasting complete response of metastatic melanoma to ipilimumab with analysis of the resident immune cells.

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POSSIBILITIES OF VACUUM THERAPY APPLICATION IN DISORDERS OF VENOUS OUTFLOW IN ISLET GRAFTS In a two-year follow-up period 53 patients developed recurrences or metastases.

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However, changes detected in this immature tissue were not associated with variations in PLC activity. L-arginine supplementation does not affect chemically induced carcinogenesis and tumor growth in BALB-c mice. Expansion of extracellular tracer spaces in the isolated heart perfused with crystalloid solutions: expansion of extracellular space, trans-sarcolemmal leakage, or both? Googling social interactions: web search engine based social network construction. Effectiveness of a balance-focused exercise program for enhancing functional fitness of older adults at risk of falling: A randomised controlled trial.

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Mandibular functional recovery and condylar remodeling are better in children with more powerful healing and reconstructing capacities. In this review, we will provide an overview of the reports published to date on the imaging and therapy of hypoxic tumors.

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Benefits of investment into modern medicines in Central-Eastern European countries. Discovery of a Small-Molecule Inhibitor of Protein-MicroRNA Interaction Using Binding Assay with a Site-Specifically Labeled Lin28. Dictyostelium discoideum is a good model system to study caspase-independent cell death where experimental accessibility of non-apoptotic cell death is easier and molecular redundancy is reduced compared with other animal models. New coarse-grained derivation of a phase field model for precipitation. While transrectal prostate biopsy is the cornerstone of prostate cancer diagnosis, serious post-biopsy infectious complications are reported to be increasing.

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To describe an outbreak of adenovirus, type 30, in a neonatal intensive care unit (NICU). Homozygotes for the ancestral A allele had impairments in the range -0.6 to -1.15 SD scores, irrespective of their diagnostic status. Overall perceived health becomes worse, but only slightly, between ages 60 and 85, whereas it appears to improve a little bit after age 85.

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Duplication of part of chromosome 17 is commonly associated with hereditary motor and sensory neuropathy type I (Charcot-Marie-Tooth disease type 1). Detection of thioamides: determination of ethionamide with 2,3-dichloro-1,4-naphthoquinone. There is a need to undertake appropriate preventive and therapeutic measures already in early childhood in order to avoid these disorders. To test this hypothesis, we induced neutral or negative affect and concurrently measured the number and precision of representations stored in sensory and working memory.

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The ISO/IEC committee in charge of standardizing the well-known MPEG audiovisual standards has launched, in cooperation with the ISO committee on Biotechnology, a new activity for efficient compressed storage and transmission of genomic information. Significant response to gemcitabine monotherapy in primary pleural epithelioid angiosarcoma. Subsequent percutaneous transhepatic cholangiographic examinations demonstrated an obstructive etiology without dilatation of the biliary system. Australian researchers need to consider the success of New Zealand and Canadian researchers, particularly given the relatively low investment in health and medical research in New Zealand.

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Focus groups were audio-recorded, transcribed and subjected to inductive thematic analysis. Colovesical Fistula Complicating Diverticular Disease: A 14-Year Experience.

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Prevention of falls should be integral, including correction in major involved factors in order to reduce fragility fracture, improve quality of life and appropriately focus clinical and economic resources. Here, we show that the paralogous gene copies evolved repeatedly through independent gene duplication events in the honeybee, bumblebee, and ant lineage. An efficient route to produce NIR light emitting Ge NCs is demonstrated. A Comparative Evaluation of Sorption, Solubility, and Compressive Strength of Three Different Glass Ionomer Cements in Artificial Saliva: An in vitro Study. The aim of this study was to assess the clinical value of SA invasion for pancreatic cancer of the body and tail.

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Following the design phase, we fabricated devices with 40, 80, and 120 microm wide control channels and evaluated the sample stream width as a function of the electric field strength ratio in the control and 1D channels (E(C)/E(1D)). A case-control study of spontaneous patellar fractures following primary total knee replacement.

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In this retrospective study, the records of 203 consecutive eyes of 191 patients who had undergone PTK at a tertiary eye care center were evaluated. Sows that had experienced tethering for about 1.5 or 4.5years and age-matched sows kept in a social housing system (loose sows) were compared.

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Long-term efficacy of TRUS-guided transperineal needle aspiration and irrigation on persistent hematospermia The physician charter on medical professionalism creates standards of ethical behaviour for physicians and has been endorsed by professional organisations worldwide. However, ST elevations in association with primary intracranial tumours are rarely reported.

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A direct infusion of amphetamine into the dorsal raphe nucleus of the rat inhibited the activity of serotonergic neurons in this site. Our retrospective study of 451 cases represent an exhaustive sample of this practice in Morocco exploring the reasons why women experience an unsafe abortion, what age group is most affected, conditions and complications inherent in this practice. In the paper by the authors the case of big size pleomorphic adenoma of the parapharyngeal space was presented. We report on a group of patients at a median follow-up of 13.9 years after salvage radiation therapy. A decrease in sialylation of glycoproteins and an increase in sialidase NEU1 were observed in LP fibroblasts.

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This paper describes the relationship between detection threshold and reaction time for pure tones presented within the context of a two-interval forced-choice signal detection paradigm. These results supported proposed mechanisms for sequence-specificity changes in DNA methyltransferases.

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Anorectal stenosis in these patients appears to be independent of active inflammation. Successful management utilizing a positive pressure technique is described and illustrated. In this paper, a method for modeling the galvanic coupling intra-body communication via handshake channel is proposed, while the corresponding parameters are discussed. Interactions between the disturbances in hepatobiliary system and the small intestine as well as their influence on the pathogenesis of PCES were estimated.

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Overexpression in Escherichia coli and functional reconstitution of anchovy trypsinogen from the bacterial inclusion body. To test whether the interaction between annulus fibrosus cells (AFCs) and endothelial cells (ECs) disrupts matrix homeostasis and stimulates production of innervation mediators. A structured review addressing the use of radiographic measures of alignment and the definition of acceptability in patients with distal radius fractures.

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The aim of this retrospective cohort study was to evaluate maternal and neonatal outcomes in patients with placenta previa (PP) and placenta accreta (PA). Mycetoma is chronic granulomatous infection of skin and subcutaneous tissue caused by nortriptyline withdrawal headaches birth both bacteria and fungi.

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