Sophivir is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Sophivir is converted to an active form by the virus itself, and the virus then uses the active form of Sophivir rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Sophivir into new viral DNA stops the production of the DNA. Virally infected cells absorb more Sophivir than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Sophivir in March 1982.
Other names for this medication:
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