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Prilactone (Spironolactone)
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Spironolactone

Prilactone is a potassium-sparing diuretic that removes excess fluid from the body in congestive heart failure, cirrhosis of the liver, and kidney disease. It also can be used in combination with other drugs to treat diuretic-induced low potassium (hypokalemia) and high blood pressure. Prilactone also is used to counteract the effects of excessive adrenal aldosterone production (hyperaldosteronism) that can occur from a tumor in the adrenal gland or enlarged adrenal glands (hyperplasia of the adrenal glands). Prilactone and its active metabolites are specific pharmacologic antagonists of aldosterone, acting primarily through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule. Prilactone causes increased amounts of sodium and water to be excreted, while potassium is retained. Prilactone acts both as a diuretic and as an antihypertensive drug by this mechanism. It may be given alone or with other diuretic agents that act more proximally in the renal tubule.

Other names for this medication:
Spironolactone, Aldactone, Aldactazide, Aldactazine, Aldazida, Aldazide, Aldozone, Alexan, Alizar, Carpiaton, Espirone, Espironolactona, Expal, Kespirona, Lanx, Letonal, Osiren, Osyrol, Practon, Prilactone, Spiractin, Spiresis, Spirix, Spiroctan, Spirolang, Spirolon, Spiron, Spirono, Spironolacton, Spironolactona, Spironolakton, Spironolattone, Spirotone, Verospiron, Xenalon,

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Regeneration of newborn intestine is implicated in neo-angiogenesis in the host, and the newborn intestinal graft is capable of mediating the survival of the maturation-incompetent 10-day-old graft. Therefore, this study aimed to analyze the influence of microscopic tumour cut-through on disease recurrence and survival and to establish clinicopathologic variables associated with tumour cut-through.

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Dividing nonadherent U937 cells displayed a shift in carboxyfluorescein (CF) fluorescence in parallel with an increased cell count indicating cell proliferation. Aerosolized ribavirin has also shown promise in treatment of patients who are severely ill with influenza A and B. This mutability of structural determinants of protective immunity is the obstacle in developing universal influenza vaccines.

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Contained Morcellation: Review of Current Methods and Future Directions. The oxyntic glands were organized into gland mass, making an oval mound elevated to the gastric lumen, in the middle of the greater curvature.

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This study, therefore, was aimed at assessing the effect of postsurgical administration of estradiol benzoate on wound healing in ovariectomized (OVX) Sprague Dawley rats. Neutralising activity and poliovirus type-specific IgA were measured in stool after a monovalent OPV type 2 challenge at 18 weeks of age. Reduction of heroin intake in baboons by an economic constraint. It is reported on the performance of dynamically orientated group talks with 5 patients with myocardial infarction and their wives within the psychic rehabilitation in phase II.

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The authors, by examining the complete body of literature for scientific evidence concerning the procedure, will describe the history of usage of these prostheses, their rationale for usage, modern devices and their results, and why they may have advantages as a treatment modality for monocompartmental knee arthritis. Percutaneous balloon valvuloplasty for severe and critical pulmonary stenosis in infants is relatively safe and effective and should be considered a valid alternative to surgical operation. A reference standard diagnosis (plus vs not plus) was defined for each eye by consensus of 5 experts at 35 to 37 weeks PMA. Modification of plant hormone levels and signaling as a tool in plant biotechnology. Rad51 inhibition sensitizes breast cancer stem cells to PARP inhibitor in triple-negative breast cancer.

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A standardized questionnaire of the International Study of Asthma and Allergies in Childhood was applied to the mothers to identify asthma in children at the age of 6 years. Breast Cancer Prevalence and Mortality among Hispanic Subgroups in the United States, 2009-2013. This experimental study demonstrated that compared with UW, HPG solution was more efficient and effective in the removal of the blood from donor kidneys and offered better protection from donor tissue damage, suggesting that the HPG solution is a promising candidate to supplant standard UW solution for donor kidney perfusion in transplantation. Although it requires more specialized glassware, high-temperature routes are generally preferred when a high degree of stability and low particle size dispersity is desired.

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Pedicle width (PW), pedicle height (PH), pedicle axis length (PAL), transverse angle (TA) and sagittal angle (SA) were measured bilaterally from C6 to T2. Thermal territories of the abdomen after caesarean section birth: infrared thermography and analysis. Inhibitory effects of glucocorticoids on increased vascular permeability caused by passive cutaneous anaphylaxis and some chemical mediators in rats. Crude incidences and relative risk estimates (Mantel-Haenszel analysis) of patients with any adverse event (AE), adverse drug reaction (ADR), serious AE (SAE), serious ADR (SADR), treatment discontinuation due to an AE or ADR, and fatal outcomes related to an AE or ADR.

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Avoiding the transplantation of grafts from donors aged over 50 years to patients with HCV infection might improve the general outcomes of liver transplantation programs. Although the initial severity of stroke is reportedly related to poor outcomes in patients with CCAD, it has not previously been directly identified as a predictor of mortality in patients with CAD or VAD. Characterization of circulating APOL1 protein complexes in African Americans. Electrocardiographic effects of dexmedetomidine in patients with congenital heart disease. To determine if DMSO is neuroprotective in ischemia, DMSO (0, 0.01, 0.03, 0.1, 0.3 and 1.0 ml) was administered intraperitoneally 30 min prior to permanent middle cerebral artery (MCA) occlusion in the rat.

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Mutants defective in synthesis, assembly, or function of chloroplast ribosomes are therefore conditionally viable. Co-administration of NVP-AEW541 and dasatinib induces mitochondrial-mediated apoptosis through Bax activation in malignant human glioma cell lines. Spongiform encephalopathies are believed to be transmitted by self-perpetuating conformational conversion of the prion protein. Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome). Diploids and tetraploids were genetically differentiated, thus corroborating the secondary origin of contact zones.

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Immunoreactive corticotropin-releasing factor (CRF) was identified and measured by radioimmunossay in rat thymic extract. Phosphorylation regulates transcription factor activity by influencing dimerization, cellular localization, activation potential, and/or DNA binding. It is important to be aware that paraspinal TB can mimic malignancy. In cases where the fistula originates close to the esophagogastric junction, the surgical possibilities are limited and one treatment option is total gastrectomy with esophagojejunal anastomosis. Evidence for leukocytospermia and its significance for male fertility

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SNAP-25 (25 kDa synaptosome-associated protein) is found in cells that release neurotransmitters and hormones, and plays a central role in the fusion of secretory vesicles with the plasma membrane. The findings of this study may be useful in providing racially specific mean cephalometric values in the planning and treatment of dento-skeletal surgery in black South African adults. The new amplatzer ductal occluder II AS achieves excellent ductal closure rates through low profile delivery systems in small infants and children with variable ductal anatomy. The technique was applied to the healing of experimental trauma produced by tape stripping, the resolution of clinical eczema and a comparison of steroid-treated and untreated tape-stripped skin. The method simultaneously takes into account the proportion of induced abortions that are censored by spontaneous abortions and vice versa in order to estimate the true annual number of spontaneous and induced abortions for a population.

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FtsZ monomers assemble to form a dynamic Z-ring at the midcell position in bacteria that coordinates bacterial cell division. These interference fringes characterize loci of equal displacement. Based on this physical model, our simulations show that arrays of ferroelectric nanosynapses can autonomously learn to recognize patterns in a predictable way, opening the path towards unsupervised learning in spiking neural networks. DNAJB6 is a constitutively expressed member of the HSP40 family.

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We additionally validate the reference genes by analysing the expression of putative candidates involved in the non-oxidative phase of the pentose phosphate pathway and in the first step of the shikimate pathway. Pediatric studies have not definitely determined predictive factors, weaning protocols, or ventilatory predictive indexes of extubation failure risk in infants with severe acute bronchiolitis. Genome-wide association studies have identified germline susceptibility loci that may account for differences between the African and non-African patients, but the lack of availability of appropriate cohorts for replication studies and the incomplete understanding of genomic architecture across populations pose major limitations.

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While the signal-to-noise ratios of distortion product otoacoustic emissions (DPOAE) in wild type mice did not change significantly during the first half-year of live, those in the heterozygous Gata3 mice decreased dramatically. Blood was obtained from healthy volunteers and from patients treated with rivaroxaban. An experience in integrated nursing education in the Paulista School of Nursing

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When examined in the context of other recent research, these findings argue for continued development and implementation of public education campaigns for organ donation, with an emphasis on repeated exposure over time. Models of eye movement control in reading and their impact on the field are discussed. The method of spectroscopy of attenuated total reflection (ATR) range was used to study the dynamics of biochemical changes of both the whole cell of Mycobacterium paraffinicum 134 and its outer layer depending on the type of growth substrate.

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Business continuity and disaster recovery: PACS as a case example. The fexofenadine and pseudoephedrine drug interactions current Stratus OCT normative database may be misleading for correct diagnosis of glaucoma in highly hyperopic children. Microbiology and antimicrobial susceptibility of peritoneal isolates were analyzed. Synergism of trimethoprim and ciprofloxacin in vitro against clinical bacterial isolates.

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The hospitals have a dual role as they also provide secondary care to their immediate catchment population. We evaluated the feasibility of a laparoendoscopic single-site lexinor norfloxacin dosage (LESS) nephroureterectomy for an upper urinary tract tumor. Effect of antagonistic bacteria and soil disinfectant on soil bacterium community in banana Fusarium wilt disease area

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