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Ladialis is a drug used to treat erectile dysfunction (ED). Ladialis was the second most popular ED drug, behind Viagra, which has sales of around $1.2 billion per year. Ladialis was the 51st biggest drug in terms of sales for the fourth quarter of 2013. Though Ladialis is in the same drug class as the other popular ED drugs Viagra, Levitra, and Staxyn, the formulation is different enough to make it unique in its effects. Unlike the other drugs in its class, which usually last four to six hours, Ladialis can work for up to 36 hours. Here’s what you should know if you’re considering taking Ladialis. Ladialis tends to take effect more quickly than other ED drugs, with onset of effectiveness within 30 minutes typically. The recommendation is to take Ladialis 30 minutes prior to sexual activity, while with Viagra and Levitra, users are instructed to take the drug 60 minutes before sexual activity. Generally, the effects of Ladialis last 24 to 36 hours after taking it. The fact that the effects are so long-lasting has been a major selling point for Ladialis, which branded itself “the weekend pill.” Many men like that they can take Ladialis Friday night, and still experience its effects Sunday morning. The extended duration of Ladialis’s effects allows for more spontaneity and less guesswork about when to take it.

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These findings highlight the synergistic beneficial results that may arise from the use of a drug delivery system, and the need to evaluate both drug candidates and delivery systems in the research and preclinical screening phases of a new cancer therapy development program. Robust, Self-Healing, and Multistimuli-Responsive Supergelator for the Visual Recognition and Separation of Short-Chain Cycloalkanes and Alkanes. In addition to JNK, p38 MAPK or ERK1/2 and ERK5 are required for mediating UV radiation- or epidermal growth factor (EGF)-induced c-Jun expression, respectively. While the overall control of each participant on the object was kept constant, the amount of cooperation along the two dimensions varied along four levels, from no (each participant controlled one dimension exclusively) to full (each participant controlled half of each dimension) cooperation. Patients were interviewed at admission regarding their HRQOL and their attitude towards disclosure of diagnosis.

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Consideration of these factors among others may broaden the scope of utility of TMS for schizophrenia as well as enhance its efficacy. discophora oxidized both iron and manganese, Sphaerotilus natans oxidized only iron and two Pseudomonas spp.

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Ultrasound scan examinations and blood pressure measurements were performed in the morning and evening. Moreover, osteopetrotic animals demonstrated an altered distribution of hemopoietic tissue with a 10-fold decrease in the number of marrow cells. Several ultrasonic tissue characterization features are known to discriminate pathological from normal tissue in vivo. Rapid waning of anti-polysaccharide bactericidal Ab and vaccine effectiveness is observed following infant immunization with the serogroup C meningococcal (MenC) glycoconjugate vaccine.

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Stem cell therapy and organ regeneration are therapeutic approaches that will, we suggest, become mainstream for the treatment of human disease. A particularly poor survival was observed for RMS of the hand/foot due its marked tendency to spread. The results on polychlorinated dibenzo-p-dioxins (PCDDs) show a large difference between G3XMP2 and previous experimental measurements and predictions using group additivity methods, semiempirical quantum chemistry, and DFT calculations, especially for highly chlorinated species. These events are monitored by the spindle checkpoint, which delays mitotic progression allowing time for corrections when errors occur in the dynamic interactions between chromosomes and microtubules. However, PKC was localized in presynaptic terminals only during the first few weeks of postnatal life, during the period when the cortex is most susceptible to visual experience.

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A recently described variant, multicentric Castleman disease (MCD), of which some cases are associated with human herpes virus-8 (HHV-8), has been reported in both HIV-seropositive and -negative patients. Familial adenomatous polyposis-related desmoid tumors can present with a liquefied center containing gas, accompanied by abdominal pain and sepsis. Radiotherapy after prostatectomy: is the evidence for dose escalation out there?

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Propofol markedly increased amplitude, decay time, and charge transfer of GABAA IPSCs. Introduction to the study of the unconscious aspects of pedodontic care Here, we attempt to summarize our current view of the mechanisms that lead to these events, regarding both additional proteins that were recently suggested to be involved, and the roles of lipids.

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This method eliminates the possibility of endogeneity bias, which may have affected the results of previous cost-effectiveness analyses on this topic. Two patients were evaluated after the intrathecal administration of an iodinated nonionic contrast agent (Isovue) and five subjects with cranial tumors following the intravenous administration of an iodinated ionic contrast medium (Renografin). Leaf pubescence in cotton have a potential for insect pest management. The carboxy part contains several diaromatic sequences that are reminiscent of motifs known to interact with clathrin adaptors. As for test-retest reliability, the values were acceptable, varying from .36 to 1.

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Gait in children with cerebral palsy: observer reliability of Physician Rating Scale and Edinburgh Visual Gait Analysis Interval Testing scale. A retrospective chart review of 44 patients who underwent eDCR between June 2012 and May 2015. The conjugate of the gossypol derivative megosin (1) with N-polyvinylpyrrolidone named rometin (2) was synthesized. Liver, muscle and adipose tissue were used to study the expression of genes involved in the synthesis and oxidation of fatty acids and lipoprotein homeostasis by real-time RT-PCR.

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In newly diagnosed hypertensive men, sCD40L levels are inversely related to insulin sensitivity, with no correlation with BP, other cardiovascular risk factors, or the degree of subclinical atherosclerosis. As indications for cardiostimulation served the Morgagni-Adams-Stocks syndrome and a well-marked circulatory insufficiency. There were no difference in patient mortality by ERI, but a significant difference in hospitalization rates and mean length of one hospitalization was revealed. Plasmapheresis is often used to treat severe cases of pemphigus.

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Oral realimentation resulted in mediastinal pain and brownish discharge within the trachea, raising the suspicion of residual gastric pouch. Ratio dependence in small number discrimination is affected by the experimental procedure.

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Evaluation of policies to promote physical activity in afterschool programs: are we meeting current benchmarks? However, the majority of patients are not managed by EDA or PCIA and cannot be ignored due to lack of knowledge of the proper use of basic analgesic treatment.

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Firstly, we present a formula for calculating the crossover rate rho for a pedigree of general structure. She had bilateral conjunctival injection, hypopyon, and severely decreased visual acuity. Several examples of genes linked by P1, and unlinked by P22, are presented. In doses of 150 and 300 microg, it has sustained benefits over 6 - 12 months with respect to both bronchodilation and patient-reported outcomes and is well-tolerated with an acceptable safety profile. A dicopper complex is described for which significant catecholase activity was found, particularly for a compound in which the two metal ions are more than 7A apart.

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Molecular dynamics simulations have been performed to study the flexibility of the glycosidic linkages. Inhibition of histidine decarboxylase in rat stomach by aminoguanidine. We performed a retrospective review of 500 consecutive sinus CTs performed at our outpatient centers. Three of the most popular stress-based rodent models are the forced swimming test, the chronic mild stress paradigm and the learned helplessness model. Karyotypes of five taxa of Rattus (Rodentia: Muridae) from Indonesia.

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Checkpoint kinase 1 (Chk1) plays a critical role in the activation of mitotic spindle checkpoint and DNA damage checkpoint. Arteriovenous malformations (AVMs) in the thalamus carry a high risk of hemorrhage. Further clinical and histopathologic data elucidated the diagnosis of fluoroscopy-induced radiation dermatitis. Imagery-related activation was only sustained for 1500ms even in control subjects, therefore, limiting conclusions regarding the ability to follow an instruction.

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A comparison of epinephrine and methoxamine for resuscitation from electromechanical dissociation in human beings. Integration of Functional MRI and White Matter Tractography in CyberKnife Radiosurgery. Patients undergoing total hip or knee arthroplasty are at increased risk of venous thromboembolism (VTE). To explore the integrated bio-control mechanism of Trichoderma harzianum and acquire some bio-control associated novel genes, a Trichoderma harzianum mycelium cDNA library has been constructed and thereby randomly selected clones were sequenced and analyzed by bioinformatics analysis. Midline tumors of the palate may represent a challenge for the maxillofacial surgeon.

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intermittent exposure did not impact the overall tolerability profile of exenatide, with no evidence of prolonged duration or worsened intensities of AEs with continuous exposure. Mice homozygous for the S50P or G22R mutation of connexin 50 have reduced amounts of connexin 50 protein at the cell membrane, with some intracellular staining consistent with retention in the endoplasmic reticulum.

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A telephone survey with contacts representing these programs was conducted between October 2005 and March 2006. Sterile porcine bile preparations, infected separately with Escherichia coli, Klebsiella pneumoniae, Enterobacter, and Enterococcus, were used as the perfusion media in an in vitro perfusion system. This study examined the speed profiles of elite wheelchair rugby (WCR) players during game-simulation training drills of differing player number and shot-clock regulations. Nondisjunctional events can lead to mosaicism in a number of ways, including failure of chromosomal pairing, failure to separate, anaphase lag and abnormal segregation.

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In order to improve the accuracy of gas quantitative analysis, it is very important to select suitable spectral resolution depending on different components and various application situations. Since IL-21 is elevated non-specifically in this cohort, our data supports that IL-21 is not an appropriate biomarker for diagnosis of KD in North American pediatric populations. The wavelength of light imposes a physical limit of approximately 400 nm on the maximum resolution that can be achieved using light microscopy.

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The fluorescence spectra are consistent with the zero-phonon hole action spectra obtained in absorption mode, the profiles of the nonresonantly burned holes as a function of fluence, as well as the fluorescence line-narrowed spectra obtained for the Q(y) band. In the case presented herein, we describe a patient treated with single-agent romidepsin at first diagnosis of AITL, resulting in complete remission for over 2 years and leading to the use of maintenance dosing. PathOS has also been deployed in cloud environments allowing multiple institutions to use separate, secure and customisable instances of the system.

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Microfluidic perfusion systems enable small-volume cell cultures under precisely controlled microenvironments, and are typically developed for cell-based high-throughput screening. Morning serum cortisol levels also were measured both before and after antidepressant treatment. Treatment selection based on biomarkers in the lymph node is a topic for further studies. The presence of uracil-DNA glycosylase in insects is dependent upon developmental complexity.

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Cardiac rehabilitation improves endurance and physical wellbeing in patients. Serum pepsinogen levels to monitor gastrointestinal nematode infections in cattle revisited. Apparently, interference effects inhibited encoding by organization and typicality.

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Increased mutagenesis in MH-mediated end joining (MMEJ) appears coupled to its slower repair kinetics and the extensive resection occurring at flanking DNA. Limited site-directed mutagenesis of specific amino acids in the SagA prepropeptide supports the designation of SLS as a bacteriocin-like toxin.

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Idiopathic Generalized Tonic-Clonic Seizures (GTCS) are frequently encountered in adults. Possibilities of combined treatment of stomach cancer with synchronous bilobate liver injury However, the lack of vaccine programs or insufficient coverage of populations in other endemic countries leaves many people susceptible to JEV. Material costs are increased because of the high cost of adhesive relative to suture.

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Electrochemical aptamer-based (E-AB) sensors offer advantageous analytical detection abilities due to their rapid response time (seconds to minutes), specificity to a target, and selectivity to function in complex media. German Anxiety Barometer-Clinical and Everyday-Life Anxieties in the General Population. Driving up the adenoma detection rate: is it time to make a U-turn?

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The transgenic tomato exhibited ethylene insensitivity phenotypes such as non-ripening and the lack of the triple response and petiole epinasty of seedlings even in the presence of exogenous ethylene. This study presents those vector-transmitted diseases that are responsible for the greatest incidence and mortality of people on a global scale. Furthermore, pycnogenol restored the PI3K antagonist-induced inhibition of glucose uptake in the presence of wartmannin, an inhibitor of the PI3K.

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Phylogenetic and morphologic analyses of a coastal fish reveals a marine biogeographic break of terrestrial origin in the southern Caribbean. We examined whether EPDME is effective for skin moisturization by means of electron paramagnetic resonance (EPR) studies of ex vivo specimens of stratum corneum (SC) obtained by successive stripping. Interlaboratory analytical comparison of fatty acid concentrations in serum or plasma. Investigating the effects of BMI on IVF-results in first treatment-cycles alone should be carried out cautiously.

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Our results indicate that both the biosynthesis of diverse metabolites and growth are promoted in proportion to the CO2 concentration at a wide range of CO2 levels, from ambient concentrations to an extremely high concentration (3,600 p.p.m.) of CO2. This paper reports on an autopsied case manifesting an esophageal cancer that had developed 13 years after radiotherapy for lung cancer.

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The virtuous effect of heat shock protein 70 and evil effect of nuclear factor-kappa B in patients with chronic gastric disease of PI-Wie damp-heat syndrome type These findings support studies that found adolescent pregnancy increases the risk of public assistance use and low educational attainment. This atlas-based algorithm quantified malalignment in complex femoral shaft fractures within clinical tolerances from a single CBCT image of the fractured limb. This brief overview of some of these lessons is written with the next generation of pioneering product developers in mind: the biologists, biochemists, and engineers who will dedicate their careers to driving medical and commercial progress in tissue engineering.

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Venous thromboembolism: indirect CT venography during CT pulmonary angiography--should the pelvis be imaged? Collected information was then used to develop a novel application of twice-as-smart ligands, as efficient chemical sensors of bacterial signaling pathways via the fluorescent detection of naturally occurring extracellular quadruplexes formed by cyclic dimeric guanosine monophosphate (c-di-GMP). Despite approximately equal numbers of male and female medical school graduates, women are entering academic medicine at a lower rate than their male colleagues. The first line of mitochondrial antioxidants is composed of superoxide dismutase and the enzymes of the ascorbate-glutathione cycle, which are not only able to scavenge ROS but also to repair cell damage and possibly serve as redox sensors.

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LSKL, a peptide antagonist of thrombospondin-1, attenuates renal interstitial fibrosis in rats with unilateral ureteral obstruction. Although activation of 5-HT-1B/1D receptors diminishes the secretion of noradrenaline from cardiac sympathetic nerves, some studies report that they may cause chest discomfort, myocardial infarction and arrhythmias due to coronary vasospasm. This study confirmed the accuracy of the EASI system in monitoring the main ECG parameters in patients admitted to the coronary care unit with acute coronary syndrome or heart failure.

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Extracorporeal membrane oxygenation therapy for postcardiotomy cardiogenic shock. Residual and/or recurrent cholesteatoma can be accurately detected by DWI MR.

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Comparison of three sequential extraction procedures for trace element partitioning in three contaminated Mediterranean soils. The principles of proportion, so important in esthetics, allow us, to calculate incisor length. Forest soils in France are sequestering substantial amounts of carbon. Mortality and morbidity after surgery of mid and low rectal cancer. Muscle is the soft tissue of choice for coverage of full-thickness chest wall defects with or without prosthetic material.

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With the construction of our biodiversity term inventory, we demonstrate that distributional semantic models are able to identify semantically similar names that are not yet recorded in existing taxonomies. Here we identify two major sources of technical variability: sampling noise and global cell-to-cell variation in sequencing efficiency. The research project used a mixture of quantitative and qualitative research methods.

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Although beta-arrestin and affiliated E3 ligases mediate agonist-stimulated lysosomal degradation of the beta(2)-adrenergic receptor (beta(2)AR), a prototypic GPCR, the molecular cues that mark receptors for ubiquitylation and the regulation of receptor degradation by the proteasome remain poorly understood. The course of HUS was complicated with hypertensive crisis, pleural effusion. Co-transplantation of endothelial progenitor cells and pancreatic islets to induce long-lasting normoglycemia in streptozotocin-treated diabetic rats. Research on the benefits of clinical medication reviews (CMRs) performed by pharmacists has been conducted mostly in controlled settings and has been widely published.

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Prevalence, persistence, and phenotypic variation of Aspergillus fumigatus in the outdoor environment in Manchester, UK, over a 2-year period. Our results demonstrate that maternal hypoglycemia is significantly associated with intrauterine growth retardation other than the low birth weight type and that the 3-hour glucose tolerance test is an effective early screening test in detecting pregnancies at risk of fetal growth retardation. Paradoxical cerebrovascular hemodynamic changes with nicardipine. To determine whether slimming effects could be transferred to obese mice, a faecal microbial transplant (FMT) was carried out, showing that host bacteria grown under a HF diet could not be superseded by those from calcium-fed animals.

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To investigate the glycoprotein determinants of viral cytopathology, we constructed chimeric env genes between a noncytopathic strain of human immunodeficiency virus type 2 (HIV-2), designated HIV-2/ST, and a highly fusogenic and cytopathic variant derived from this virus. We reviewed the records of 604 consecutive patients who underwent complete resection for non-small cell lung carcinoma of the lower lobe. The SPSS 10.0 software (Bizinsight, Beijing China) was used for oxetol 300 mg wikipedia encyclopedia statistical analysis. A extranodal pulmonary immunocytoma that originated from the lung is reported.

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The binding of vinblastine to both human and rabbit platelets was identical with maximal binding occurring within 10 min at 600 microgram/ml servamox 500 mg vinblastine. We developed a spatio-temporal model of the growing eye disc based on the regulatory interactions controlled by the signals Decapentaplegic (Dpp), Hedgehog (Hh) and the transcription factor Homothorax (Hth) and explored how the signaling patterns affect the movement of the MF and impact on eye disc growth.

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From Genetics to Genomics: A Short Introduction for Pediatric Neurologists. All these zitrim forte posologia loratadina treatments produced long-term changes in more than one test.

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On the basis of these results, a possible growth mechanism for the formation of flowerlike ZnO nanostructures was described. In an attempt to screen FXR agonists, we found that cycloastragenol (CAG), a natural occurring compound in Astragali Radix, stimulated FXR transcription activity. Theory of dipolar relaxation in aqueous macromolecular solutions. An insertion/deletion polymorphism of the dihydrofolate reductase (DHFR) gene is associated with serum and red blood generic finasteride buy uk cell folate concentrations in women. Histologic analysis of the joints of Prg4(-/-) mice showed an enlarged, fragmented surface layer of variable thickness with Safranin O-positive formations sometimes present, a roughened underlying articular cartilage surface, and a progressive loss of pericellular proteoglycans.

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The present findings suggest that OP agents induce plasma hypertriglyceridemia in mouse through single or dual inhibition of FAAH or/and MAGL, apparently leading to overstimulation of cannabinoid signal regulating energy metabolism. gabexal 300 mg gabapentin d03 Importantly, IVIg is used clinically for the treatment of several auto-immune neuropathies, such as Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy (CIPD) and Kawasaki disease, with a good safety profile. The results support the view that the fetus is associated with the pre-partum prolactin pulse in maternal plasma and that a prolactin pulse at this stage is luteolytic in non-pregnant tammars. The adoption of a multi-tier approach will allow countries to select the baseline method best suiting their specific capabilities and data availability while simultaneously ensuring scientific transparency, environmental effectiveness and broad political support.

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All subjects underwent conventional MRI and esomeprazole magnesium dihydrate synthesis of dibenzalacetone complementary MTI analysis to compose histograms. Functional outcome after resection of spinal cord hemangioblastomas associated with von Hippel-Lindau disease. Clinical symptoms were mainly otorrhagia and conductive hearing loss.

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An effective radiotherapy device for treatment of residual or suspicious cancer in the enucleated orbit consists of an external-beam radiation source (60Co) and an intraoperatively fitted mould as a guide for the flexible afterloading tubes using a 192Ir nizoral cream yeast infection source. This study compared AVF post-creation procedures and their associated costs in patients with SAVF to patients with a new endovascularly created AVF (endoAVF). Based on this analysis, recommendations are given to improve the translational power of brain ischemia-related experimental research. Formulation and Evaluation of In-vitro Characterization of Gastic-Mucoadhesive Microparticles/Discs Containing Metformin Hydrochloride.

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The next steps in competency-based medical omeprazole mylan patient information leaflet education: milestones, entrustable professional activities and observable practice activities. Bifunctional spectroscopic probes were designed to make use of adaptable-anchor and length-varied spacers to estimate molecular distances by exploiting short-range collisional electron transfer. Comparative characteristics of the force and rate of myocardial contraction as indices of its contractility Experimental studies on the pathological pulmonary changes in burn-blast combined injury

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Other than the uncommon mucinous cystadenoma of the ovary presenting in adolescence, MCNs are rarely seen by the pediatric pathologist. This initial psychometric investigation of the FPAS suggests that the primordial performance toco 8 vs propecia FPAS may be useful in both clinical and research settings to assess patient acceptance of implantable cardiac devices. This study investigated the effects and Numerical Rating Pain Scale (NRS) of using absorbable shanching satin rb-bFGF prepreg sheet and expansion hemostatic sponge together nasal packing in the control of epistaxis with blood disease, and compared it with traditional vaseline gauze. Radiological and clinical effect of prosthesis design in varus knees? Impact of Multi-Night Experimentally Induced Short Sleep on Adolescent Performance in a Simulated Classroom.