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Canadian Journal of Cardiology in 2014: from percutaneous intervention to regenerative medicine. The anticancer drug cisplatin (CP)-induced nephrotoxicity associated with apoptosis plays crucial roles in tumor patients.

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Yet, despite the use of molecularly targeted drugs with well defined targets, to date there are no biomarkers to guide the use of antiangiogenic therapy in patients. LC-PDA and LC-ESI-MS separation and determination of process-related substances arising from stilbene-type fluorescent whitening agents. An experimental study on the wear of HDP socket in total hip arthroplasty--quantification of worn surface by SEM 3-D image analysis and effect of gamma-ray-irradiation of HDP on improving tolerance to wear

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RA treatment increased the expression of gas3 and caused gas2 to be transiently overexpressed in amino-acid-deficient medium. Short amplexus duration in a territorial anuran: a possible adaptation in response to male-male competition. Postoperative exacerbation of chronic obstructive pulmonary disease.

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During the last decade, the spectre of an influenza pandemic of avian origin has led to a revision of national and global pandemic preparedness plans and has stressed the need for more efficient influenza vaccines and manufacturing practices. Upon oxidant challenge, Yap1 accumulates rapidly in the nucleus where it activates expression of genes required for oxidative stress tolerance such as the thioredoxin TRX2. The facets of relationship marketing are explored, with the greatest emphasis placed on internal marketing. Histochemical demonstration of sulphate groups by means of diaminobenzidine. Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation.

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Varicella Complications in Unvaccinated Children and Delay in Hospital Admission. In young athletes (30 years old and younger) structural cardiovascular disease, often congenital, is usually responsible. N-Oxidation of the metabolite, TRAA, by human liver microsomes was much slower than that of tiaramide. The Ground Waters of Vermont from a Chemical and Bacteriological Standpoint. We present the new BALOO package for performing multireference variational/perturbative computations for medium- to large-size systems.

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A literature search was performed (for drugs and DDSs against VL) on PubMed and through Google. The relationship between cervical enamel projection and class II furcation defects in humans. Traditional concept of madness and therapeutic difficulties in the Moose of Kadiogo.

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Pre-mRNA splicing is regulated by developmental and environmental cues, but little is known about how specific signals are transduced in mammalian cells to regulate this critical gene expression step. We evaluate genetic test plantations of North American Douglas-fir provenances in Europe to quantify how tree populations respond when subjected to climate regime shifts, and we examined whether bioclimate envelope models developed for North America to guide assisted migration under climate change can retrospectively predict the success of these provenance transfers to Europe.

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In all three studies, the whole scale and subscale scores of females were significantly higher than for males. Recent studies showed that LPL mass in non-heparinized serum (LPLm) was an index of LPL-mediated lipolysis of plasma triacylglycerol (TG).

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Patch-clamp recordings in each region were used to measure both the synaptic and the intrinsic electrical properties. No signs of heart failure or cardiac friction rub were evidenced. Thus, a clinical follow up of patients with functional vocal impairments and analysis of cause-and-effect relationships prompt the conclusion that functional dysphonia is a neurotic symptom whereas laryngeal alterations are secondary to pathological voice production. During the period between 1981 to 1985, 40,243 children have been born. Daytime sleep contributed to retention of source memory rather than item memory in females, whereas males undergoing daytime sleep had a trend towards increased familiarity.

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Heparin-binding epidermal growth factor-like growth factor improves intestinal barrier function and reduces mortality in a murine model of peritonitis. To test this, participants received a modified version of the Stroop task, in which they were either briefly cued with the goal of naming the color or meaning of targets on a trial-by-trial basis. Results of treatment of trachoma with vaccine and long-acting sulphonamide combinations compared with the vaccine and the sulphonamide alone.

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This article reviews clinical and epidemiological studies that have described a link between depression and the subsequent development of IHD and have examined the role of depression as a predictor of cardiac events in patients with existing IHD. Previous work has shown that there are perturbations in the enteroendocrine cell population of macroscopically normal crypts, a compartment not included in existing models. For the sine vocoders, peaks in the FFRTFS spectra corresponded with the low-frequency sine-wave carriers and side band frequencies in the stimulus spectra. Targeting improved patient outcomes using innovative product listing agreements: a survey of Canadian and international key opinion leaders. However, little is known about the role of the local factors which exist in the bone matrix.

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enterica cultures contain subpopulations of opvABOFF and opvABON cells. Here, a surface-enhanced Raman scattering (SERS)-based immunoassay, using magnetic beads and SERS nano tags, was developed for the determination of free to total (f/t) prostate specific antigen (PSA) ratio to improve the diagnostic performance of prostate cancer. Non-electron-deficient isoalloxazines without an N-3-alkyl mercaptan side chain did not catalyze m-nitrothiophenol oxidation.

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In myotubes from C2 cells, LN is concentrated within the majority of spontaneous acetylcholine receptor (AChR) aggregates. Disclosure of psychosocial concerns of young adults with advanced cystic fibrosis (CF) by a nurse home visiting program. Childhood dermatological problems contribute about one-third of all consultations in the setting of both pediatrics and dermatology outpatient services. Although recurrent fever was noted among both MAC infected and uninfected patients, weight loss greater than 20 lb, weakness, anorexia, abdominal pain, and diarrhea were more frequent among infected patients. This process has been associated with increased binding of Ikaros to the upstream regulatory element of TdT.

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ARMS2 and HTRA1 mRNA levels did not show a significant difference in expression among the control (young and elderly) and AMD retinas. Qualitative and quantitative neurohistological changes produced in the rat brain by prolonged aerogenic hypoxia in early ontogeny.

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A random sample of 200 healthy individuals without femoral fracture were also identified. Cationic antimicrobial peptides as potential new therapeutic agents in neonates and children: a review. Recombinant human lubricin was shown to produce significant improvement in both signs and symptoms of dry eye disease as compared to HA.

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In response to pressure overload induced-hypertrophy, the decrease in insoluble collagen incorporation in the left ventricle of SPARC-null hearts was coincident with diminished ventricular stiffness in comparison to WT mice with pressure overload. Functional activation protocols are widely applied for the study of brain-cognition relations. In conclusion, use of the new mouse genetic map has improved the localization of mouse BMD QTLs, and these remapped QTLs show high concordance with human GWAS loci.

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The delay phenomenon in types of deltopectoral flap studied by xenon-133. The association is much stronger using objective assessment compared to questionnaire.

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Treatment with KI and/or its combination with tetracycline may be a useful treatment for PPP/PAO. Antifibrinolytic therapy of gynecologic hemorrhages (literature survey) Quantifying the forces guiding microbial cell adhesion using single-cell force spectroscopy. The number of experiments performed under identical conditions allows a correlation of the separation factors alpha(m) with the interaction strengths Rm. Although the theory behind the reflectivity of symmetric mirrors has been well studied, little is known about asymmetric mirror designs.

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NMR-spin echo and dielectric studies of water in biopolymers have been carried out. We have shown that there has been a considerable increase in the rate of use of ICT in general practice in recent years, but these rates have fallen behind targets set by the NHS IT Strategy.

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One important aspect is the comparison of CEUS with magnetic resonance imaging (MRI). Recombinant human myxovirus resistance protein A (MxA) was successfully expressed by an Escherichia coli expression system. The isolates, the first reported from marine mammals in the Antarctic region, were identified as Campylobacter insulaenigrae and Campylobacter lari.

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All common FTD-causing genes have seemingly now been discovered and the main pathological proteins identified. When radioactively labelled fully developed Pasteurella (P.) multocida antigens were parenterally applied to mouse, through intravenous, intraperitoneal or subcutaneous routes, activity distribution was found to depend both the technique of application and the radionuclide used. In the first two sheep where the needle was not well aligned with the marking catheter, the ASD was in the septum secundum. Risk assessments for acute violence to third parties: a review of the literature. It may present in atypical size and clinical appearance in patients with altered or impaired immunity and rarely in immuncompetent patients.

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Selected articles were measured based on the inclusion criteria of this study and initially compared in terms of titles or abstracts. Its role in the central nervous system (CNS) is still unknown, even if its involvement in brain damage and neurotoxicity has been postulated. The purpose of this study was to evaluate the in vitro macrophage compatibility, the inflammatory response and in vivo host response to a novel collagen-chitosan (COL-CS) scaffold containing growth factors incorporated Chitosan Nanoparticle (CNP). The hardness of dentin in laser group was higher than the bur group because of the higher mineral content of the dentin. Bipolar long-stem prosthetic replacement for the treatment of comminuted intertrochanteric fractures in the elderly osteoporotic patients proves to be a suitable alternative.

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Oligodendroglioma, usually found in the cerebral hemispheres may invade the ventricles, however primary intraventricular oligodendroglioma is quite uncommon with only a limited number of cases reported in the literature. This work related the solvent type to the energy efficiency as the first step of a complex study aiming to assess the energy balance of sonochemical reactors at 500 kHz. Phasic heart rate change and the U-shaped relationship between choice reaction time and auditory signal intensity. 7 The inter-ethnic differences found could be due to both environmental and genetic factors.

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Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders. Thanks to the laser, high definition photographic plates, and an achromatic compensation phenomenon applicable to equal inclination fringes, the spectrometric method, based on an analysis of Fabry-Perot rings through an adapted grid, is now simple to use, as shown in this paper.

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A chemogenomic approach to understand the antifungal action of Lichen-derived vulpinic acid. Unanticipated consequences primarily occurred when bars did comply with the law and smokers went outside the bar to smoke, particularly when smokers stood on the street outside the bar.

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Behavior of physicians and clients in a voluntary program of testing for the Tay-Sachs gene. Furthermore, after a reexposure to cocaine after long-term withdrawal, the membrane excitability of NAcSh MSNs instantly returned to a normal level in intraperitoneally pretreated rats.

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As only a small number of doses are given, TLR agonists as vaccine adjuvants appear to hold greater potential and have less safety concerns than for other applications. A mathematical model for our deposition method allows us to determine the parameters for a protein adsorption model and then predict the final shape of the surface density gradient.

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Human electrophysiological reflections of the recruitment of perceptual processing during actions that engage memory. Aquaporins play key roles in tumor biology and are involved in cell growth, migration and formation of ascites via increased water permeability of micro-vessels.

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Our results show that there is a better outcome for a patient with an aortic root diameter between 3.0 and 3.5 cm with early prophylactic surgery than with deferred or emergency surgery. Understanding the mechanisms of tumor development and progression is critical to developing improved therapies aimed at better survival. There is no specific quality of life (QoL) measurement tool to quantify QoL in patients with biliary tract cancer.

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Numerous steps are required to successfully complete a revision total knee arthroplasty. The effects of phenazine methosulfate (PMS), a known generator of oxygen free radicals, on ion transport in human erythrocytes were studied. Can Endoscopic Ulcerations in Early Gastric Cancer Be Clearly Defined before Endoscopic Resection? Differences in DNA from the male and female of the same species also can be measured. The month-2 culture conversion used in phase 2 clinical trials as surrogate marker of treatment efficacy is influenced by the culture method used for monitoring mycobacterial response to TB treatment.

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Cell rubidium uptake: a method for studying functional heterogeneity in the nephron. At the theoretical level, sufferance is imaging in the valuing connecting-separating of transforming.

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Results shown in the present paper are discussed in light of results obtained in other work on human tissues using the same sources of antibodies. This method has proved particularly valuable when dealing with deep lying vessels which are neither visible nor palpable. Recruiting Children for Clinical Trials: Lessons From Pediatric Oncology.

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Elucidation of the mechanism of the 1,6-cuprate addition to acceptor-substituted enymes through 13C kinetic isotope effects: experimental and theoretical studies. The evidence presented is interpreted as indicating that diarrhoea results in endogenous, de novo synthesis of nitrites, and this is the principal cause of infantile methemoglobinemia. We present a mathematical model of oxide formation and growth on platinum.

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We conclude that terbutaline is not helpful in differentiating temporary from anatomic tubal obstruction during HSG. Conducting a larger randomized controlled trial would be feasible. Discourse comprehension in L2: Making sense of what is not explicitly said.

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Subjects were randomized to receive prospectively either a relaxation session or a mildly stressful interview first. Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study. Structural characterization of partially folded intermediates of apomyoglobin H64F. Disseminated histoplasmosis with colonic ulcers in a patient receiving infliximab.