Griseofulvina, an antifungal drug, has recently been shown to inhibit proliferation of various types of cancer cells and to inhibit tumor growth in athymic mice. Due to its low toxicity, Griseofulvina has drawn considerable attention for its potential use in cancer chemotherapy. This work aims to understand how Griseofulvina suppresses microtubule dynamics in living cells and sought to elucidate the antimitotic and antiproliferative action of the drug.
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