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Checking the linear transformation model for clustered failure time observations. A control group was selected among patients with bilaterally normal uterine artery PI.

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Our experience with the use of nonvascularized iliac crest bone graft is hereby reported. This proved to be due to a haemorrhage into a large trigeminal neurinoma.

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Cardiovascular disease is an inflammatory process and the leading cause of death in the United States. The questions were related to preoperative imaging, indications and timing of surgery, technical choices, and the influence of patient-related aspects.

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This study investigated the effects of resveratrol (RV) on diabetes-related metabolic changes in a spontaneous model of type 2 diabetes, as well as activation of AMP-activated protein kinase (AMPK) and downstream targets. Whereas successful university spinoffs tend to emphasize the scientific value of their knowledge and gain reputation through their high-quality publications, other successful firms tend to emphasize the commercial value of their knowledge and gain reputation through high-quality patents.

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Further mechanism study showed that, by binding to histone demethylase lysine-specific demethylase 1 (LSD1), an enhancer of zeste homolog 2 (EZH2), IRAIN reduced PC tumor cell apoptosis and induced growth arrest by silencing the expression of Kruppel-like factor 2 (KLF2) and P15. First isolation of Histoplasma capsulatum from the urban bat Eumops bonariensis These findings strengthen the notion that widespread streptococcal ICEs may form mosaics that enhance their diversity and spread, broaden their host range and carry new cargo genes.

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Mollusks were dominated in abundance in Poyang Lake and the rivers connected to Shijiu Lake, while oligochaetes dominated the communities in Shijiu Lake. Protein kinase B (PKB) and mitogen-activated protein kinase (MAPK) were both initially phosphorylated and activated by FGF-1 treatment, but when phosphorylated MAPK reached maximal activation, phosphorylated PKB was at its lowest levels, suggesting an interaction between MAPK kinase (MEK-1/2) and phosphatidyl inositol-3-kinase (PI3K) during Egr-1 induction. These results suggest that the improvement of focal cerebral ischemia by lacidipine may be partly due to long-lasting improvement of collateral blood supply to the ischemic area. The naevoid basal cell carcinoma syndrome (NBCCS) is a therapeutic challenge due to the multiplicity of cutaneous tumours.

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These cases emphasise the potential for serious hepatic reactions with nitrofurantoin, the danger of continuing the drug once liver damage has occurred and the need for careful monitoring of liver function during long-term therapy. Outlining and quantifying this phenomenon is important to interpret routine and pullback pressure measurements within the coronary tree. Delivery Unit, Tampere University Hospital, Finland, with 5200 annual deliveries.

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Isolated DNA repeat region from fcrA76, the Fc-binding protein gene from an M-type 76 strain of group A streptococci, encodes a protein with Fc-binding activity. The alkaloid toxin quinine and its derivative compounds have been used for many centuries as effective medications for the prevention and treatment of malaria.

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The sonographic shape of intracerebral hemorrhage correlated closely with the area of increased density seen on the CT scan. In the present study, we have developed linear and cyclic fibrin-binding peptides for thrombus imaging and compared their biological properties. The objective of this study was to determine the clinical comparative effectiveness and adverse event rates of posterior minimally invasive surgery (MIS) compared with open transforaminal or posterior lumbar interbody fusion (TLIF/PLIF). Ventral midbrain neural stem cells have delayed neurogenic potential in vitro. The H2AS40Gc site is in the L1 loop structure where two H2A molecules interact in the nucleosome.

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A decrease in the extracellular ferrous iron by an iron chelator and incubation with purified ceruloplasmin in the culture medium prevented hepcidin-mediated ferroportin internalization, while the reconstitution of apo-ceruloplasmin was not able to prevent ferroportin internalization. The use of plethysmography and oscillometry to compare long-acting bronchodilators in patients with COPD.

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From these results, we showed that AG induces excessive lipid accumulation and mitochondrial damage in zona fasciculata cells, which leads to an accelerated lysosomal degradation in mice. In one pregnancy a normal fetus was diagnosed from studies of cultured amniotic fluid cells and the diagnosis confirmed after the baby was born. Evaluation of receptor functionality may be useful in screening for susceptibility. Chylothorax and fibrosing pleuritis secondary to thyrotoxic cardiomyopathy. Using data from the Longitudinal Sample of Working Lives, which includes information about the labour market trajectory of Spanish workers, survival models are employed to analyse the duration of employment periods of workers with disabilities.

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Impact of Membrane Drug Transporters on Resistance to Small-Molecule Tyrosine Kinase Inhibitors. Two types of households: with poor hygiene and with good hygiene, were studied.

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The interplay between these cells is complex and not fully understood. A 3-week hiking vacation at moderate or low altitude is safe for patients with metabolic syndrome and provides several improvements in their cardiovascular parameters. Plastid-derived signals are known to coordinate expression of nuclear genes encoding plastid-localized proteins in a process termed retrograde signaling. The influence of atherosclerosis and plasma D-dimer concentration in patients with a functioning arteriovenous fistula for maintenance hemodialysis.

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Positron annihilation lifetime spectroscopy (PALS), a method well established for the study of polymers, is employed to characterize the temperature dependence of the free volume through T(g) in the amorphous pharmaceutical Verapamil hydrochloride. Emerging evidence from human and animal studies suggests that exercise is a highly effective treatment for drug addiction. Noggin elicits retinal fate in Xenopus animal cap embryonic stem cells. Understanding the delicate balance between bleeding and thrombosis: can we use it to our advantage?

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Homeobox genes may have direct or indirect influence on their transcription levels but can also interact with those components via protein-protein interaction. Substantial progress is expected from emerging technologies, but the largest challenge remains to carry out in situ whole-tree labelling experiments on mature trees to improve our understanding of the environmental and physiological controls on C allocation. Elimination of inter-domain interactions increases the cleavage fidelity of the restriction endonuclease DraIII.

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Motivational enhancement therapy is based on established motivational principles for treating patients with addictive disorders and has been adapted as an early component of treatment for patients with anorexia nervosa and bulimia nervosa. We report the use of intraductal ultrasound to facilitate therapeutic biliary interventions in four critically ill patients in an intensive care unit. The vaginal route is a safe, feasible, and patient-friendly method of performing a hysterectomy. A series of microarray analyses showed that the inferred SskA-HogA-AtfA pathway is implicated in the transcriptional response to osmotic stress as well as fludioxonil. Long-distance communication in the HDV ribozyme: insights from molecular dynamics and experiments.

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Compared to other more common neurological diseases, CMS are rare. Molecular phylogeny of the cyprinid tribe Labeonini (Teleostei: Cypriniformes). Results from structural equation modeling indicate that each of the mediators in our study accounts for a significant portion of the effect of parenting on the quality of adult romantic relationships, although the constructs linking parenting to warm interactions with romantic partners are somewhat different from those that link parenting to hostile interactions with romantic partners. Nursing informatics is a combination of computer science, information science and nursing science designed to support the practice and delivery of patient care. Serum anti-C1q antibody is a valuable noninvasive biological marker for evaluation of renal involvement and lupus prognosis.

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Double-blind randomised-controlled trial of Losartan 50 mg once a day versus placebo for 96 weeks in patients with histological evidence of NASH. Girls of all ethnicities had identical growth trajectories and reported higher initial school belonging than Euro-American or Latino boys. Novel functional role of heat shock protein 90 in protein kinase C-mediated ischemic postconditioning.

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EEG and behavioural patterns induced by intraventricularly administration of cathinone in rats. An increase in hematocrit appears to have an adverse effect on CsA lymphocyte binding. We confirm the feasibility of protein-only mediated mechanical gating by demonstrating that the interaction between TonB and BtuB (a TBDT) is sufficiently strong under force to create a channel through the TBDT.

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Induction of oocyte maturation by hyaluronan-CD44 interaction in pigs. Patient factors associated with incidents of aggression in a general inpatient setting. The human periodontium health is commonly compromised by chronic inflammatory conditions and has become a major public health concern. It was caused by feeding a BARF diet containing thyroidal tissue in one dog and by conventional dog food in the other patient. The study was funded by grant R01 CA151973 from the National Cancer Institute, National Institutes of Health, USA.