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Depakote (Divalproex)
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Divalproex

Depakote was originally developed as an anti-seizure medication. In the last 15 years we have found that it also affects mood. Like other “mood stabilizers”, Depakote can prevent large or rapid changes in mood. It does not seem to have any effect on day to day mood changes, only “cyclic” or unprovoked changes. It also has powerful effects on anxiety, agitation, insomnia, panic symptoms, and anger.

Other names for this medication:
Divalproex, Depakote, Dicorate, Divaa, Desval,

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Patients undergoing TPE for colorectal tumors have improved survival when compared with patients undergoing exenteration for pelvic malignancies of other origins. Radiographic outcomes were analyzed via Combine radiograph findings, while NFL performance outcomes were assessed for all Lisfranc injuries (2009-2013) compared with matched controls in the first 2 years of play.

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A semi-quantitative agreement between data obtained by surface sampling and that by employing organ homogenate extraction was observed. This study has also yielded a more precise location for the rifampin resistance gene. Thirty-nine ovariectomized gerbils were physically trained to swim in a 90 cm-diameter round pool.

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A range of programs was developed using several types of signal processing algorithms, allowing simultaneous one-dimensional and two-dimensional representation of motor acts of the head and eye, including separate analysis of slow and rapid movements. In order to facilitate further the use of the system, a technique for cell-free construction of recombinants was established using rolling circle amplification and biolistic inoculation of DNA B-transgenic plants.

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Targeted ablation of AGER diminishes the amount of autophagic flux and attenuates the development of early pancreatic intraepithelial neoplasia (PanIN) lesions in a murine model of KRAS-drivien carcinogenesis. At the mineralization front of the epiphyseal growth plate large quantities of calcium (Ca) are necessary to form the mineral (a Ca-phosphate). The precision of this transducer has been evaluated as compared to a conventional force displacement transducer (FDT) in the present study. Recent data suggest that colonic secretion postbacterial infection is mediated by galanin-1 receptors (Gal1-R). Healthcare workers (HCW) are at increased risk of infection during pandemics.

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Repair Strength in Simulated Restorations of Methacrylate- or Silorane-Based Composite Resins. This adaptive response could be inhibited by cycloheximide, a protein synthesis inhibitor for successive 2 h period ranging from 0.5h before to 4h after the low dose exposure, indicating that the adaptive response was directly related with the protein synthesis.

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We therefore determined the rate of each failure mode and the survivorship of revision THAs. A set of convergent antibodies of highly similar sequences found in the VAT of HFD mice but not RD mice showed significant somatic mutation, suggesting a response shared between mice to a common antigen or antigens.

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CmABCG1 had significantly higher expression in the haemolymph and head compared to the other tissues. We evaluated the expression of seven therapy-related genes to predict the clinical outcome of advanced gastric cancer patients treated with a neoadjuvant chemotherapeutic protocol. We present a case of growth and spontaneous regression of a middle cerebral artery aneurysm after surgical clipping. Lateral Segregation of Photosystem I in Cyanobacterial Thylakoids. Clearance of antigen from the blood of mice was accelerated following injection of an optimal dose of precipitating antibody but co-precipitating antibody was ineffective even at different doses.

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The CpxA/R two-component signal transduction system of Escherichia coli can combat a variety of extracytoplasmic protein-mediated toxicities. CAP-induced release of SP and CGRP from the renal pelvis was less in DS-HS compared to other groups. Prior studies have shown that all of these multimerizing APOBEC3 proteins, but not the monomeric family members, have the capacity to package into HIV-1 particles and restrict viral infectivity. The Ontology of Biological and Clinical Statistics (OBCS) for standardized and reproducible statistical analysis. We found a functional ERE corresponding to the sequence GGGGCAnnnTAACCT (rtvtgERE), which differs from the consensus ERE (ERE(cs)) by three base pairs.

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This retrospective study evaluates gastric aspiration as an inexpensive and safe alternative to endoscopic or radiographic confirmation. These results suggest that the PD-induced hyperleptinaemia could, in part, be mediated by the effect of glucose-based dialysis fluids on leptin production by adipocytes via activation of the hexosamine biosynthetic pathway.

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Growth inhibitory, bactericidal, and morphostructural effects of dehydrocostus lactone from Magnolia sieboldii Leaves on antibiotic-susceptible and -resistant strains of Helicobacter pylori. Sequence characterization, polymorphism, and tissue expression profile of an effector immediate-early gene: activity-regulated cytoskeletal associated protein gene (Arc/Arg3.1) in swamp and river buffalo. Maximum amplitude and the shortest latency were observed at accelerations 100 times higher than threshold ones.

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Their characterisation on the atomic scale has proven essential for progress in synthesis as well as for the theoretical modelling of their physical properties. To survey the use of long-lasting expanding gases in ophthalmology in Japan. Although none have been firmly established as dominant, it is generally agreed that casuistry, or the case-based method, is one important strategy commonly used for resolving ethical issues. Our results suggest that the Ad5.HA HPAI vaccine is safe and effective, with the potential of cross-clade protection.

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Continuous measuring of heat production during the course of the day in fully grown rats at different nutrition levels and different environmental temperatures Fosfomycin showed a high degree of activity among the 116 anaerobic bacteria tested. The assigned values of all comparisons were traceable to the primary standards of the Czech Metrology Institute (CMI). The effect of pretreating the milk (centrifugation, pasteurization-homogenization and churning) was studied by double-staining the surface of the milk fat globules, followed by observation using CLSM, and by determining the phospholipid profile of raw milk, raw cream, processed milk and buttermilk powder.

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Native and solubilized decellularized extracellular matrix: A critical assessment of their potential for improving the expansion of mesenchymal stem cells. Vitrectomy with gas is an efficient and safe treatment for uncomplicated PRD. Thus, the SMN complex forms stable associations with both nuclear and cytoplasmic snRNPs, and plays a critical role in their biogenesis. Nonsuicidal self-injury (NSSI) among adolescents poses a significant problem for schools, adolescents, and their families. Determinants of alpha-fetoprotein levels in patients with hepatocellular carcinoma: implications for its clinical use.

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Other PPARgamma-agonists, such as troglitazone and ciglitazone, did not inhibit IL-6 signaling, indicating that 15d-PGJ(2) affect the IL-6-induced Jak-Stat signaling pathway via PPARgamma-independent mechanism. They are relatively rare in the gastrointestinal tract and affect the oesophagus most commonly. The method is based on addition of phase-mismatched segments within a phase-matched medium. To our knowledge, these results are the first demonstration in a physiological context that insulin signaling through Akt controls a specific cell division program and leads to the physiologic generation of binucleated tetraploid liver cells.

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Quantitative subcellular study of transferrin receptor-targeted doxorubicin and its metabolite in human breast cancer cells. The absence of fluorescence and appearance of structured phosphorescence at 77 K are attributed to nitrophenyl-localized lowest energy singlet and triplet states. However, JNK Inhibitor II, a specific inhibitor of c-Jun N-terminal kinase (JNK) prevented the IL-1beta mRNA expression induced by Y4 CP in a concentration-dependent manner.

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In the present study, we demonstrated the functional importance of lncRNA MEG3 in proliferation and angiogenesis of VECs. Especially in cases of recurrent abnormal uterine bleeding, recurrent abortion, and infertility, PDUS can be preferred as a first-line diagnostic method. Collectively, these results open the way to further functional analyses to better characterize Bti-resistance mechanisms in mosquitoes. Our pharmacist-managed, ED-based outpatient treatment program for VTE disease is safe, effective and achieves a high level of patient satisfaction.

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fMRI signals corresponding to this selective advantage included greater activity in lateral prefrontal cortex (LPFC), hippocampus, and dorsal striatum for young adults relative to children. In vivo pharmacokinetics and safety of CN-100, a propionic acid derivative non-steroidal anti-inflammatory drug (NSAID), were investigated in 12 healthy male volunteers with single oral administration at a dose of 150 or 300 mg, or repetitive oral administrations at a daily dose of 300 mg. This worldwide shift is increasingly accumulating pressure on UAE pharmacists to turn up into better level of service providing accompanied with higher demand of inter-personal skills and intellectual capabilities. Conduction pathway of pi-stacked ethylbenzene molecular wires on Si(100). The most probable explanation for the loss of vitamin C from plasma was an increased urinary excretion during operation.

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Probabilistic neural-network structure determination for pattern classification. Results suggest that retail clinics play a growing role in vaccination delivery, and vaccinations constitute a substantial share of the business conducted by retail clinics.

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This project provides valuable information about primary care teaching at an undergraduate level across the UK. The development of three long universal nuclear protein-coding locus markers and their application to osteichthyan phylogenetics with nested PCR. Strong leaders possess qualities that inspire others to follow them. Post-Concussion Symptom Scale (PCSS) total score, maximum symptom-free heart rate (SFHR) during graded exercise testing (GXT), GXT duration, balance error scoring system (BESS) score, and number of adverse events. More study is suggested among women of color who may have higher body burden levels of these compounds.

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burgdorferi strains with mutations in DNA repair genes for increased susceptibility to ROS or RNS in vitro. We herein report a case of ICC coinciding with a liver metastasis from a known rectal carcinoma. For this purpose, silver ions were selectively added to the scaffold surfaces through ion-exchange using an aqueous silver nitrate solution. For minimally invasive thymectomy, video-.assisted thoracoscopic surgery has been the preferred surgical approach till recently. The wheat-germ cell-free protein synthesis system had been one of the most efficient eukaryotic cell-free systems since it was first developed in 1964.

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Wild-type p53-induced phosphatase 1 is a prognostic marker and therapeutic target in bladder transitional cell carcinoma. The results of the studies in 120 patients after resection of tumours located in cranial fossa (40 cases), basal-diencephalic area (45 cases), hemispheres (35 cases) have shown the role of brain edema in the onset of critical conditions after neurosurgery (with consideration of a new concept concerning the mechanisms of brain edema development). A similar nocturnal maximum can be observed for the concentrations and elimination rates of total protein, potassium and bicarbonate, while the concentration of sodium is fairly constant and only slightly decreasing in very high flow rates. This information is important to assist parental counseling in pregnancy.

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We applied this approach to the Pyrenean desman (Galemys pyrenaicus), a semiaquatic and endangered species endemic to the Iberian Peninsula. However, the literature provides evidence of inadequate prescribing practices by dentists, due to a number of factors ranging from inadequate knowledge to social factors. Pianists showed greater gray matter (GM) volume in bilateral putamen (extending also to hippocampus and amygdala), right thalamus, bilateral lingual gyri and left superior temporal gyrus, but a GM volume shrinkage in the right supramarginal, right superior temporal and right postcentral gyri, when compared to non-musician controls. Differentiation of pre-osteoblast cells on poly(ethylene terephthalate) grafted with RGD and/or BMPs mimetic peptides. While the magnitude of the superadiabatic force is small if the system evolves from an equilibrium state inside of a parabolic external potential, it is large for particles with equidistant initial separations at high temperature.

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Small hairpin RNA (shRNA) was used to knockdown the SHANK2 in SCAPs. Contribution of the auxiliary staff in the care of children with skin and pleuropulmonary staphylococcal infections Chromatin is partly honeycomb-shaped and partly highly condensed. Forced expression of Apr-1 inhibited cell proliferation of cholangiocarcinoma cell line QBC939 and induced G2/M phase arrest.

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The international tea cartel during the Great Depression, 1929-1933. European brown hare syndrome in free-living mountain hares (Lepus timidus) and European brown hares (Lepus europaeus) in Finland 1990-2002. Role of Demyelination Efficiency within Acellular Nerve Scaffolds during Nerve Regeneration across Peripheral Defects.

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Synthesis and structure-activity relationships of antimalarial 4-oxo-3-carboxyl quinolones. Surveillance study for creating the national clinical database relating to ECG-gated myocardial perfusion SPECT of asymptomatic ischemic heart disease in patients with type-2 diabetes mellitus: J-ACCESS 2 study design.

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Red cell concentrates were stored in SAGM, AS-1, AS-3 or PAGGSM, and sampled fourteen times spanning Day 1-46. The therapeutic outcome for those with malignant glioma is poor, even though diverse therapeutic modalities have been developed. During follow-up, relapse rate and changes in EDSS were comparable between both patient groups, with differences seen between different types of IFN-beta drug application. In this case, the mass media require an amplitude threshold in order to overcome the influence of the leader and drive the system into a dynamically disordered state. Key steps in the process are the generation of millions of sequence reads from an infected tissue sample, followed by assembly of these reads into longer, contiguous stretches of nucleotide sequences, and then identification of the contigs by matching them to known databases, such as those stored at GenBank or Ensembl.

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Fecal counts of Muellerius, Nematorirus and coccidia were not associated with the results of either assay. High mobility group box (HMGB) proteins of Plasmodium falciparum: DNA binding proteins with pro-inflammatory activity. Thus, it is possible to purify a conformationally relevant form of rabies virus glycoprotein that contains only one N-glycan with a substantial reduction in its microheterogeneity. Nerve terminals containing clear vesicles were observed in synaptic contact with glomus cells at this phase. We conducted a cohort study using information from the General Practice Research Database.

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Confounding between groups should be of more concern than confounding within groups in partially ecologic analyses. Nuclear localization of the rat glucocorticosteroid receptor (rGR) transiently expressed in COS-7 cells appears to be mediated by two nuclear localization signals, NL1 and NL2, in a hormone-dependent mechanism. Percutaneous endoscopic gastrostomy (PEG) using the introducer technique is not only useful in patients with upper digestive tract stenosis but has been shown to reduce peristomal infection.

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The FE results suggest that implementation of viscoelastic properties may not be necessary for computational studies of skull behaviour during masticatory loading but instead might be more relevant for studies examining lower frequency physiological activities. The correlation between anterior cruciate ligament injury in elite alpine skiers and their parents.

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Acetal derivatives are easily obtained from 1,2-difunctionalized compounds by a new reaction mediated by IPy2BF4 with a mechanism based on a 1,2-migration of aryl or alkyl groups. Two-dimensional jaw tracking and EMG recording system implanted in the freely moving rabbit. It may thus contribute to chronic skin inflammation in atopic as well as in nonatopic persons.

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Clustered localization of STAT3 during the cell cycle detected by super-resolution fluorescence microscopy. Histological examination revealed an increase in cell death at the effective concentrations on the neuroepithelium and branchial bars mesenchyme.

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A metered-dose inhaler (MDI) with spacer is the best way to deliver bronchodilator therapy for treatment of bronchoobstructive syndrome, especially in children. Chromatin immunoprecipitation assay revealed a direct interaction of KLF6 with iNOS promoter during in vitro and in vivo flu infection of human lung cells and mouse respiratory tract, respectively.

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We tested a series of consecutive cases of mucosal LP in our clinic by enzyme-linked immunosorbent assay using desmoglein 3 (Dsg3) and BP180 fusion proteins. Intraoperative gamma probe detection was achieved for the invaded bone, dura, and periorbit of sphenoid wing meningiomas. The device makes the determination of the position of wells and the filling process as a whole since these scales may be moved just to the wells. The PI3K pathway has the most frequent activating genetic events in HNSCC (especially HPV-positive driven), but the differential signaling between CSCs and non-CSCs is also unknown. Contribution of intestinal cytochrome p450-mediated metabolism to drug-drug inhibition and induction interactions.

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These criteria were tested for all 19 mokomokai repatriated to New Zealand by the French authorities. The treatment was considered successful when b-hCG concentrations dropped to less than 0.2 mIU/ml without surgery. Administration of prostaglandin E(1) also increased the turnover rate of 5-hydroxytryptamine and raised the concentration of acetylcholine in brain.3. In this review, we explore the preclinical rational for this synergism and the potential consequences for immunotherapy in oncology. Cyanoacetylene has been detected in the interstellar medium as well as simulated prebiotic experiments.

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Two hundred and forty-four proteins were highly expressed, while 263 proteins exhibited lower levels of expression, in the U251 cells compared to the U87 cells. While the majority of the viral genome became relatively quiescent, the latency-associated transcript was specifically upregulated. Phylogenetic analysis revealed that all mecC-MRSA isolates from both farm animals and workers formed a separate cluster, whereas human isolates from the same municipality belonged to a closely related cluster. Human immunodeficiency virus type 1 (HIV-1) efficiently enters cells of Old World monkeys but encounters a block before reverse transcription.

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It was concluded that highly skilled archers do not predominantly reflect a release consistent with the coaching canon and that factors other than the string release mechanism discriminate the performances of skilled archers. One brother and one sister, of seven siblings, had cirsoid aneurysms of the occipital scalp with underlying skull defects and possible intracranial communication.

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Parkinsonian patients have a tendency to speed up during repetitive motor tasks (festination) and to experience sudden motor blocks (freezing). This study aimed to report on the clinical and radiographic response after partial caries removal on left mandibular primary second molar. To evaluate the utility and safety of a short-type double-balloon endoscope (DBE) in the treatment of biliary disease in patients with surgically altered gastrointestinal (GI) anatomy. A retrospective case-control study was performed at our institution involving consecutive ADPKD and non-ADPKD chronic kidney disease (CKD) patients seen over a 13 year period with both chest CT and PFT.

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The pharmacokinetic parameters of oseltamivir carboxylate, the active metabolite of oseltamivir, were not significantly different between obese and nonobese subjects for both 75-mg and 150-mg doses. Regardless of the absence and presence of ultrasound, the adsorption isotherms were well obeyed by the Langmuir equation.

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A new, nondestructive, highly sensitive method for colorimetric monitoring of primary amines, secondary amines, and thiols on a solid support was developed. In general, the big challenge of nanotechnology, particularly for nanomedicine (nano-bioengineering), is to understand which nano-specific characteristics interact with particular biological systems and functions in order to optimize the therapeutic potential and reduce the undesired responses. The changes in plasma protein, pH and kilox medicine electrolytes from the hemodilution beginning to surgery finish were monitored.

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The relationship of chronic pain, mental illness and organic disorders. Administration of 500 mg of SB to dairy cows every cefpodoxime proxetil 200 mg dispersible vs soluble 14 d increases the efficiency of milk production. P-113 peptide: New experimental evidences on its biological activity and conformational insights from molecular dynamics simulations. Photoperiod regulates multiple gene expression in the suprachiasmatic nuclei and pars tuberalis of the Siberian hamster (Phodopus sungorus). Assessment of SAT thickness in routine echocardiographic examinations might be used in predicting the existence of MS and its associated cardiovascular risks.

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Consistent with these findings, we show that Spt5 is physically associated with RNA Pol II in vivo, and have claromycin antibiotic identified a region of sequence similarity between Spt5 and NusG, an Escherichia coli transcription elongation factor that binds directly to RNA polymerase. These results suggest that SG-ex exerts anti-hyperglycemic effects in rats by inhibiting maltase activity and that these effects are at least partially exerted by its sweet elements, triterpene glycosides. FOLFOX4 regimen has advantages in cases with lower HSP70 expression over those with higher HSP70 expression. For an estimation of adaptability it is necessary to use a complex of attributes (morphological, cytogenetic, resistance to abiotic and biotic factors of environment). Poster 149 Diagnosis of an Ulnar Nerve Foreign Body by Ultrasound: A Case Report.

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Hip protector use in elderly institutionalized residents in Germany is highly cost-effective. We retrospectively analyzed the group of 117 patients hospitalized with the clinical diagnosis of acute appendicitis. Before treatment, pantoprazole infusion adverse effects magnifying endoscopic observation was performed. To our knowledge we are the first to propose the metallic profile. The ultrasound technique used into bronchial space let us obtain fully reliable material from places previously inaccessible to pneumonologist.

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Vibrio vulnificus is an important pathogen which can cause serious infections in humans. Although long-term data are not available, the conviction of those who participated in the experiment is that such a purpose was and can be uniquely fulfilled. The activities of monensin, disulfiram effect lasalocid and halofuginone against Eimeria tenella, E. Two PEDF protein peaks were identified after anion-exchange column chromatography: PEDF-1 eluting with lower ionic strength than PEDF-2. Studying behaviour and cognition may improve diagnosis and prognosis, allows recognition of comorbidities, and contributes to adequate counselling of families.

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Numerous innovations conceming the difficult problems of ascending aortic surgery appear regularly in the literature. A group of 4 pregnant rats were sacrificed at each day over the period from 12 to 17 successive days of pregnancy. Digital Gene Expression Profiling to Explore Differentially Expressed Genes Associated with Terpenoid Biosynthesis during Fruit Development in Litsea cubeba. In select patients, minimally invasive transthoracic device closure of juxtaarterial ventricular septal defects appears to flagenase 400 pediatrico suspension dosis cataflam be safe and effective, with good midterm outcomes.

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