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In addition, it is demonstrated that LeuO, a LysR-type transcription factor, binds to two sites flanking the casA promoter and the H-NS nucleation site, resulting in derepression of casABCDE12 transcription. This study shows a differential expression of ion channel genes involved in cardiac contraction in DCM that might partly underlie the changes in left ventricular function observed in these patients.

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Fabrication of a Highly Sensitive Single Aligned TiO2 and Gold Nanoparticle Embedded TiO2 Nano-Fiber Gas Sensor. Therefore, the influence of this drug on ciliary function should be considered when nasal topically applied.

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Antibodies against these regions were examined by peptide-based enzyme-linked immunoassay in sera of 90 patients with PBC and 40 with chronic hepatitis C (CHC), 21 with non-alcoholic steatohepatitis (NASH), 10 with primary sclerosing cholangitis (PSC), 14 with obstructive jaundice, 10 with drug-induced liver injury and 42 healthy controls. SPA from IC sites was associated with aversion, generalized seizures and catalepsy.

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Organic acids produced by self-sustaining coacervates in presence of p-nitroaniline and p-phenylene-diamine. In this review we consider an essential but largely ignored overlay to that blueprint, the human microbiome, which is composed of those microbes that live in and on our bodies. It is possible to cure the patients with XLSA by gene therapy because it is a single gene disorder. Localization of neurons innervating edible snail columellar muscles

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A short German Physical-Self-Concept Questionnaire for elementary school children (PSCQ-C): Factorial validity and measurement invariance across gender. Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy. This indicated that it is important to restore normal limb offset without overlengthening to obtain adequate soft-tissue tension in total hip arthroplasty.

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Identification of predictive markers of response to chemotherapy is a challenging approach for drug selection. Prototype of a new tip developed to be coupled to dental light-curing units for optimizing bonding of orthodontic brackets and accessories. We present here the new algorithm MIMSTATS, which performs an analysis of these images and determines whether the variations in the images are statistically significant. Among the new permanent cements, glass ionomer which has a low solubility is the most interesting one.

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The Effects of Antipsychotics on Prolactin and Bone Mineral Density. This complex behavior leads to a multi-stage aggregation mechanism which we have termed multi-domain misfolding.

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Different from the decreasing thiol group content upon time in acidic condition, increasing amount of thiol groups was detected in alkaline pH during 120 min dialysis attributed to alkaline hydrolysis of intra-molecular disulfide bonds. Preventing oxidative damage in the heart is subject of considerable investigation and studies developing nutritional intervention methods to attenuate or prevent the resulting pathological state of free radical damage are now emerging. Pretreatment with DPCPX or epsilonV1-2 inhibited psideltaRACK-induced cardioprotection and translocation of epsilonPKC. Clinical efficacy and safety of uterine artery chemoembolization in abnormal placental implantation complicated with postpartum hemorrhage No revertant viruses were found, and there was no evidence for transmission of virus to unvaccinated volunteers housed in the close contact with the vaccinees.

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Control of occupational dermatitis in the German Democratic Republic Panduratin A showed stronger activity than epigallocatechin 3- O-gallate (EGCG) known as a natural anti-aging agent. Effects of exposure to mixed organic solvents on blood pressure in non-smoking women working in a pharmaceutical company. The identification of this pathway enabled the construction of an HMF and furfural-metabolizing Pseudomonas putida. A retrospective, population-based study design was used to examine seasonal and temporal patterns of croup hospitalizations from April 1, 1988, to March 31, 2002.

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The Grice procedure: indications and evaluation of long-term results. Spontaneous, undisplaced fractures occurred in the long bones of five patients with longstanding rheumatoid arthritis. These data suggest that PBL rosette formation with measles- or mumps-infected cells may represent nonspecific adherence rather than specific adherence. Effect of osteosynthesis, primary hemiarthroplasty, and non-surgical management for displaced four-part fractures of the proximal humerus in elderly: a multi-centre, randomised clinical trial. Other ion channels are specially designed for modulation of the action potential shape.

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DRG cells (L3-L5) were cultured and supernatants collected for fractalkine (FKN) ELISA. Redescriptions are provided for Sphyriocephalus tergestinus Pintner, 1913 and S. These alterations have clinical consequences for the infected patient, including an increased risk for cardiovascular diseases, and an impaired protection against the formation of antibiotic-resistant bacterial biofilms. To investigate whether there are differences in brain connectivity in late-life depression (LLD) and nondepressed subjects using the left and right heads of caudate nuclei (hCN) as the seed regions.

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The functions for some VZV glycoproteins are known, such as gB, gH and gL in membrane fusion, cell-cell fusion regulation, and receptor binding properties. We find that the statistical energies of the Potts model are correlated with the fitness of individual proteins containing therapy-associated mutations as estimated by in vitro measurements of protein stability and viral infectivity.

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All five underwent successful venipuncture after sonographic localization of a vein. Multiple regression is used to assess the independent effects of predictors. Women with NHI in Taiwan undergoing various types of hysterectomy to treat noncancerous lesions. Clinical data were collected using the Community Periodontal Index (CPI) and the decayed, missing and filled teeth (DMFT) index.

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Clinical and molecular pathology of aggressive Schneiderian papilloma involving the temporal bone. Four-compartment fasciotomy of the lower extremity without fibulectomy: a new approach. Denitrification was highly variable across urban ecosystem types, but no significant differences were found between urban and reference denitrification rates. Such findings highlight the need for the rehabilitation of patients with multiple ankle sprains to include proprioceptive and balance training. A reappraisal of ICU and long-term outcome of allogeneic hematopoietic stem cell transplantation patients and reassessment of prognosis factors: results of a 5-year cohort study (2009-2013).

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Endometrial washings histological and cytological assessment of material obtained with an intrauterine jet washing device. Development of an autonomous biological cell manipulator with single-cell electroporation and visual servoing capabilities. Case report in an adult intensive care unit of a tertiary care hospital.

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After that, we started treatment with voriconazole per os 200 mg twice a day. The reduction of MDA in the liver is suggested to be an unspecific metabolic reaction to the drugs that express cytotoxic, in particular hepatotoxic, effects associated with oxidative stress and lipid peroxidation. We identified 171 patients at 2 hospitals between 5/10/2005 and 8/31/2012 with two CPC scores at hospital discharge recorded independently - in an in-house quality improvement database and as part of a national registry.

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No antithrombotic therapy has been shown to reduce mortality when used with thrombolytics in acute myocardial infarction (AMI). Today, more and more children with complex heart lesions and underlying cardiomyopathies reach adulthood. The aim of this study is to establish a prediction scoring system for inferior mesenteric artery (IMA) lymph node metastasis and to assess the prognostic impact of dissection of positive IMA node on patients with stage III rectal cancer.

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Cognitive dysfunction in adult survivors of allogeneic marrow transplantation: relationship to dose of total body irradiation. The possibility that thyroid hormone is a major physiological regulator of the synthesis of RNA polymerase I in rat liver is discussed. The effect of copolymer blend ratios and TFE/VP ratios on membrane properties were evaluated, and the stability of P(TFE-VP) in PVDF membrane was studied. What is the standard of care for patients with left main stenosis? On-chip incubation of SH-SY5Y cells with racemic DOPA was carried out, and the incubation solution was injected and in-line assayed at time intervals.

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Parents play an important role in the dental behavior of a child patient. Wound healing: a paradigm for lumen narrowing after arterial reconstruction. In particular in septic shock other mechanisms have to be involved.

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Improving self-report measures of medication non-adherence using a cheating detection extension of the randomised-response-technique. However, multicenter randomized trials and studies involving a long-term follow-up are necessary.

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NMIIa and actin filaments concentrate around LDs, and form transient foci between dissociating LDs. Several database search engines that can be accessed via the World Wide Web are described. It has been proposed that pyrogens may produce their febrile response by the release of prostaglandins in the hypothalamus. The average rT3 level was decreased in both goitrous groups and the difference between them was significant. Positron emission tomography/Computed tomography is clinically valuable for a variety of gynecologic cancers.

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Results confirmed the predictive validity of the ASVAB and showed that one of the AT-SAT subtests resembling a low-fidelity ATC work sample significantly improved prediction of training performance beyond the ASVAB alone. Adaptive servoventilation (ASV) has demonstrated efficacy in treating sleep-disordered breathing (SDB) in patients with heart failure (HF), but large randomized trials are lacking. Arteriography demonstrated a fistula between the proximal superior mesenteric artery and vein with significant portal hypertension. The high-affinity character of the binding is reflected in the adsorption isotherms and is further illustrated by their non-extractability with high concentrations of Tween 20.

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Functional Single-Walled Carbon Nanotubes and Nanoengineered Networks for Organic- and Perovskite-Solar-Cell Applications. The cellular proteins were abstracted from human breast cell line MDA-MB-231 for analysis with Western blotting using quick (2 h) and slow (overnight) protein transfer, different blotting membranes (nitrocellulose, PVDF and nylon membranes) and different visualization methods (ECL and DAB). Control conditions to realize all the six connecting states of a 3 x 3 switch are discussed with the solution of the coupling equation for those guides. These results imply that absorptive and secretory processes occur within the same epithelial compartment.

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In obesity oxidative stress is thought to contribute to the development of insulin resistance, non-alcoholic fatty liver disease and the progression to non-alcoholic steatohepatitis. Whereas many studies have described HMO patterns in human milk from larger cohorts, data on the excretion of HMO and possible metabolites produced in the infant gut are still very limited.

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The data show that road traffic injuries are significantly more numerous than either police or hospital sources indicate. Nsp1p does not contain a Ran-binding domain and therefore represents a distinct type of nucleoporin that associates with Gsp1p. Causality of small and large intestinal microbiota in weight regulation and insulin resistance.

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Surprisingly, considerable growth and development can occur in the absence of both dMyc and dMnt. Intraocular straylight is known to originate from the cornea, lens and fundus. A Phase Ib Study of the Dual PI3K/mTOR Inhibitor Dactolisib (BEZ235) Combined with Everolimus in Patients with Advanced Solid Malignancies. Saving a life: balancing risks, harms, and benefits in palliative care.

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Photonic bandgap fibers with resonant structures for tailoring the dispersion. Isolation and characterization of LexA mutant repressors with enhanced DNA binding affinity.

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The third method was the enhancement of endothelialization by immobilization of bio-signal molecules. Cigarette smoking may be reduced significantly among pregnant, methadone-maintained women through the use of contingent reinforcement for gradual reductions in breath carbon monoxide levels. Machine learning techniques for single nucleotide polymorphism--disease classification models in schizophrenia. The ability of dolastatin 15 and eight modifications or precursors thereof to inhibit the growth of a Gram-negative bacterium suggests that these compounds have an additional target distinct from tubulin.

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In a rat model of hypoxia-induced pulmonary hypertension, daily oral dosing of animals with GW0742 (30 mg/kg) for 3 weeks significantly reduced the associated right heart hypertrophy and right ventricular systolic pressure. The secreted glycoprotein osteopontin (OPN) sets into motion an astounding variety of activities that range from bone remodeling via immunomodulation to the inhibition of apoptosis. Probucol reduces the rate of association of apolipoprotein C-III with dimyristoylphosphatidylcholine. The role of motivational interviewing in improving linkage was not supported.

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Voltage-gated sodium and calcium channels in nerve, muscle, and heart. The association between peak urine flow rate and progression to incident lower urinary tract symptoms, defined as the first of medical treatment, surgery or sustained and clinically significant lower urinary tract symptoms, was tested by multivariable Cox models, adjusting for various baseline characteristics and treatment arm.