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Both ICS combined with SRT and double-dose ICS had the same effect on asthma control, improving symptoms and ameliorating lung function. To what degree does adenotonsillectomy affect neurocognitive performance in children with obstructive sleep apnea hypopnea syndrome due to adenotonsillar enlargement?

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The reduced accumulation of Abeta in APP/FE65 double transgenics, compared with APP mice, could be linked to the low Abeta42 level observed at 4 months of age and to the lower APP-CTFs levels. However, when comparing rats following status epilepticus with control rats we identified 13 differentially expressed miRNAs with miRNA-187-3p being most strongly regulated. Assessing and controlling microbial contamination in cell cultures.

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Although experimental research is important, the emphasis should be on clinical development. Intraaneurysmal GDC Embolization for Ruptured Aneurysm in the Acute Stage. Careful planning undergirds success when performing any implant therapy. The development of new classes of electronic, energy-storage, and information-technology devices depends critically on understanding and controlling field-induced polarization switching.

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The protein expressions of Fas and FasL were determined by immunohistochemistry staining analysis after culture for 24 hours and 48 hours. Based on phylogenetic analysis, this CugP-type UDP-glucose pyrophosphorylase may have recently been horizontally transferred to certain noncyanobacteria. Repeated intravenous doses tended to be cleared from the blood univormly. Primary tumours of the ureter are to be regarded as rare tumours. We investigated the rate of vitamin D deficiency in patients treated for periprosthetic joint infection and whether vitamin D deficiency is independent of other risk factors for vitamin D deficiency in patients with periprosthetic joint infection.

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On the basis of these results, it is suggested that progressive retention of hippuric acid, indoxyl sulfate, and other yet unidentified inhibitors may explain the gradual increase in urinary fractional excretion of urate observed in uremia. Attenuation of myocardial injury by postconditioning: role of hypoxia inducible factor-1alpha. Protein kinase C-dependent activation of CaV1.2 channels selectively controls human TH2-lymphocyte functions. Detection of increased vasa vasorum in artery walls: Improving CT number accuracy using image deconvolution. Staff training in marketing and operation of PA programs is needed.

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Obituary: Lionel Edgar Mawdesley-Thomas (February 23, 1931 - August 30, 1974). Regulation of complexin 1 and complexin 2 in the developing human prefrontal cortex. These data can be used to determine the appropriateness of treatment at 12 weeks and aid the decision to introduce biologic DMARD. Physiologically-based toxicokinetic models help identifying the key factors affecting contaminant uptake during flood events. Effect of peritoneal dialysis modality on the 1-year rate of decline of residual renal function.

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The patient underwent evacuation of the arachnoid cyst by a partial membranectomy without any beneficial effect, and finally got rid of the hemifacial spasm by reexploration and microvascular decompression of the facial nerve. C Histomorphology of neuromuscular junction in Duchenne muscular dystrophy. Therefore, our results demonstrate that contact with host cells increased bacterial susceptibility to tobramycin. Preoperative embolization of intracranial meningiomas: efficacy, technical considerations, and complications. We consider that haploinsufficiency not limited to LETM1 but including other genes acts as a risk factor for the WHS-associated seizure disorder, according to a comorbidity model of pathogenesis.

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Therefore, CelE1 was found to be promising candidate for use as detergent additives. 3, several groups of rats underwent a single 1-h session of restraint at various time intervals prior to injection with morphine (4.0 mg/kg) and tail-flick testing. The low catalytic turnover rates of LPMOs necessitate the use of sensitive product detection methods, which limits the analytical possibilities considerably.

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Mitochondrial shape is cell-type specific and can be modified to meet changing requirements in energy production, calcium homeostasis, lipid biogenesis, fatty acid synthesis and other mitochondrial activities. This pathological state was accompanied by disturbances of the complex pathogenesis. Even though Doxil showed no anti-tumor activity, the dual-ligand LP suppressed tumor growth because the disruption of tumor vessels was efficiently induced.

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Previous uncontrolled studies have suggested that SCD leads to a high rate of neonatal jaundice. Cooperative activation of D1 and D2 dopamine receptors enhances a hyperpolarization-activated inward current in layer I interneurons. Thyroid hormones were found to be decreased acute period following burns but staying in normal levels. Low-density lipoprotein subfraction, carotid artery intima-media thickness, nitric oxide, and tumor necrosis factor alpha are associated with newly diagnosed ischemic stroke.

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For example, maternal smoking impairs human placental development by changing the balance between cytotrophoblast (CTB) proliferation and differentiation. Subtracting the background activity in VOI(2)-VOI(1) from VOI(1) yields SAM. We develop a new model to simulate nonradiative relaxation and dephasing by combining real-time Hartree-Fock and density functional theory (DFT) with our recent open-systems theory of electronic dynamics. Stability of the phenotypic reversion of x-ray transformed C3H/10T1/2 cells depends on cellular proliferation after subcultivation at low cell density.

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The newly designed nanocarrier shows greater internalization (about 8 times) due to magnetic field. Letter: Need for research for protective measures against chronic chemical injury. Clathrin-coated pits and vesicles represent the major ports of entry into most eukaryotic cells. Understanding these differences will help clinicians and health educators engage MSM in dialogue to increase condom use in situations where it is warranted.

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These consisted of the proximal 15 cm of the duplex-confirmed, refluxing proximal greater saphenous vein, one proximal lesser saphenous vein, and one midportion of greater saphenous vein. A novel purification method for multipotential skeletal stem cells.

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Carotid intima-media thickness (CIMT) and carotid atherosclerotic plaque (CAP) are well-known indicators of atherosclerosis. No differences were evident between anhedonic and control subjects at the two short onset asynchronies nor were there any significant between-group differences when the interval between stimuli was long (2000 ms). Exertion electrocardiography and coronarography in 25 patients with apparently primary myocardiopathies Bacterial extracellular polysaccharides have been shown to mediate many of the cell-to-cell and cell-to-surface interactions that are required for the formation, cohesion and stabilization of bacterial biofilms.

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Design of vascular endothelium-specific drug-targeting strategies for the treatment of cancer. The field of drug epidemiology based upon sewer sampling has only emerged in the last 10 years and has great potential to aid in drug epidemiological studies.

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These images were compared with double balloon enteroscopic findings and/or resected specimens. In 50 women and 57 men aged 20 to 80 years serum levels of T3, T4 and rT3 as well as TSH levels before and after intravenous application of TRH and serum triglycerid- and cholesterol-levels were determined. Spontaneous synchronization has long served as a paradigm for behavioral uniformity that can emerge from interactions in complex systems. The data during the Glacial show large fluctuations in the atmospheric carbon-14 content, related to changes in global environment and in cosmogenic isotope production. A number of dogs were studied using a monitoring device which consists of an X-Ray beam collimator, collimated sodium iodide dectetors and their associated electronics.

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The density of the aggregation increased up to PND 9, but then decreased gradually, finally becoming unrecognizable at around PND 15 in both groups. The results of our experiments showed that acoustic waveguides were well suited for measurements in most Newtonian fluids, in agreement with earlier research presented in the literature. It is expected that the use of the measurement of salivary cortisol will become routine in the evaluation of patients with disorders of the HPA axis.

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Tolerance of perioperative anemia, which is one of the main components of blood conservation, does not increase the risk of complications or death in cardiac surgery. The adenylate cyclase activity of CyaA was necessary for its modulatory effects on murine innate immune cells. The ocular pathology of trisomy 22: report of two cases and review. Microbial alginate dressings show improved binding capacity for pathophysiological factors in chronic wounds compared to commercial alginate dressings of marine origin.

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Serial blood samples were collected for 144 hours after each warfarin dose. Our findings may lay the groundwork for future therapeutics based on transplantation of genetically engineered human primary cells for treatment of diseases affecting kidneys and potentially other tissues. The predominant inhibitory effect was observed during 4-7th hour after viral adsorption using viral production assay.

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The selection of patients for reconstruction following mastectomy for carcinoma of the breast. Aspirin is one of the most frequently used and cheapest drugs in medicine.

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Two dichotomized variables were considered as risk sexual behaviors: two or more sexual partners in the last twelve months, and occasional use of condom in the last three sexual relations. Osteochondrosis of the intermediate cuneiform is a rare entity that may cause foot pain and limping in children.

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This study utilized metabolomic profiling to examine the pathogenic mechanisms of ALD based on a rat model. IDO is expressed in primary MMCs to a low degree and is unlikely to play a direct major role in vivo in dampening antitumor immunity.

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Whether these ethnic differences result from a teacher rating bias or reflect actual classroom behavior patterns is unknown. Important genes that lie in these DNA regions may be implicated in the pathogenesis of congenital teratomas.

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Representation of binaural spatial cues in field L of the barn owl forebrain. RadList/Entity-link List ( www.tnt-radiology.de/radlist and www.tnt-radiology.de/entitylinklist ) is conducive to quality improvement and benefits users as well as authors of radiological teaching files on the Internet. 1990 report of the American Association of Poison Control Centers: poisonings in animals. Fabrication of fullerene-decorated carbon nanotubes and their application in flame-retarding polypropylene.

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Furthermore, silencing hexokinase II of LoVo cells induced loss of mitochondrial membrane potential, activation of caspase-3, and inhibition of thymidylate synthase expression. Complex vocal signals, such as birdsong, contain acoustic elements that differ in both order and duration. The gene was isolated by a combination of mutant complementation and biochemical approaches, and its function was demonstrated by heterologous expression in Escherichia coli under the control of a T7 RNA polymerase promoter. Rectal indomethacin (200 mg) resulted in a riseof cardiac sphincter pressure, suggesting that endogenous synthesis of an inhibitory (E-type) prostaglandin was suppressed.

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Following Mac1-sap treatment there was a near total loss of microglia, these microglia-depleted cultures displayed a significant increase in PI uptake and astrogliosis 1 day after OGD compared to non-depleted cultures. We asked whether FOXM1 expression is also responsive to obesity in human islets by collecting RNA from human islet donors (body mass index range: 24-51). This paper develops a rigorous analysis of the microtubule elastic deformations in terms of the torsional degrees of freedom using the helix-based cylindrical structure of this biopolymer. Effects of blood levels of tetracycline and oxytetracycline on hepatic and renal functions in normal subjects.

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We describe a novel minimally invasive modality in a 20 month toddler-transesophageal bronchoscopic ultrasound-guided fine-needle aspiration (EUS-B-FNA). Subjective measures of consciousness in artificial grammar learning task.

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This layer cannot be explained by traditional continuum theories. In this paper, we show how to interpret the nonstationarity due to a smoothly changing variance in terms of higher order cross-cumulants. IFN-alpha treatment led to increased gp96 expression in a time- and dose-dependent manner.

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PPI: independent study questions savings through use of generic drugs Four cases are presented in which either biopsy or laparotomy of a CT-detected mass after therapy revealed fibrous tissue with no evidence of viable neoplasm. STAT3 activation in response to growth factors or cytokines participates in retina precursor proliferation. Identification of HIV-infected youth and linkage to care can be major challenges.

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Phylogenetics of social behavior in Australian gall-forming thrips: evidence from mitochondrial DNA sequence, adult morphology and behavior, and gall morphology. The observations of long-term neurological and functional improvement provide evidence that some ameliorative change may be occurring concurrently with progressive degeneration. Recent developments of diagnostic modalities have increased detection of many benign and low malignant pancreatic lesions, and then various minimally invasive surgeries and/or pancreatic function preserving surgeries have been devised for such lesions. Surgery is the first line of therapy, with variable benefit from adjuvant chemotherapy or radiation when total resection is not possible.

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Phenolic-rich lychee (Litchi chinensis Sonn.) pulp extracts offer hepatoprotection against restraint stress-induced liver injury in mice by modulating mitochondrial dysfunction. Deficiency of TLR4 in donor, but not in recipient, inhibited NF-kappaB activation, reduced proinflammatory cytokines and improved viability of islet grafts. Lipid-soluble fractions revealed a ciguatoxin-like activity in both in vivo (mouse bioassay) and in vitro (mouse neuroblastoma cells assay and receptor binding assay using tritiated brevetoxin-3) assays. At baseline, the physical/neurological examinations, standard clinical assessment, neuropsychological testing, and assessment of motivational variables were performed. Numerous varicosities are characteristic for the tubular lysosomes whose similarity with grumose bodies has lead to conclusion that the vermiculate variety of the latter are almost certainly tubular lysosomes.

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It is thus believed that these glucose diffusivities, as well as their variation with cell line, may have important implications for the role played by glucose in the growth and cellular heterogeneity of spheroids and tumors. mirabilis communicates IdsD between neighboring cells for nonlethal kin recognition, which suggests that the Ids proteins constitute a type of cell-cell communication. Patients with advanced metastatic soft tissue sarcoma (STS) have a poor prognosis, and in the last two decades of the 20th century their overall survival has remained unchanged. The mean exposure of all studied substances was higher than occupational exposure limits. Primary epithelial cell cultures derived from canine prostate: isolation, culture, and characterization.